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1.
Nano Lett ; 24(13): 3906-3913, 2024 Apr 03.
Artículo en Inglés | MEDLINE | ID: mdl-38506264

RESUMEN

The intriguing and anomalous optical characteristics of exceptional points (EPs) in optical resonators have attracted significant attention. While EP-related phenomena have been observed by perturbing resonators with off-chip components, implementing EPs fully on-chip remains challenging due to their extreme susceptibility to fabrication errors. In this Letter, we propose a succinct and compact approach to reach EP in an on-chip integrated silicon microring resonator by manipulating the evolution of backscatterings with two nanocylinders of disparate diameters. The theoretical analysis unveils that the fabrication constraints could be significantly relieved by increasing the difference in diameters of the nanocylinders. The evolution from non-EP to EP is traced experimentally through the step-by-step tuning of the angular and radial positions of nanocylinders. The proposed method opens a pathway toward the on-chip high-density integration of non-Hermitian devices.

2.
Opt Express ; 32(6): 10274-10283, 2024 Mar 11.
Artículo en Inglés | MEDLINE | ID: mdl-38571243

RESUMEN

In this paper, we propose a novel bimodal waveguide based on regional mode engineering (BiMW-RME). Leveraging the orthogonality of the guided modes, the form of patterned SiO2 cladding on the bimodal waveguide can reduce the interaction between the reference mode and the analyte, thereby significantly improving sensitivity. The proposed BiMW-RME sensor experimentally demonstrates a phase sensitivity of 2766 π rad/RIU/cm and a detection limit of 2.44×1-5 RIU. The sensitivity is 2.7 times higher than that of the conventional BiMW sensor on the same SOI platform. The proposed design strategy demonstrates a significant improvement in the sensor's sensitivity, presenting a novel approach to enhancing common-path interferometric sensor performance.

3.
Opt Lett ; 49(7): 1741-1744, 2024 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-38560851

RESUMEN

Speckle-correlation optical scattering imaging (SCOSI) has shown the potential for non-invasive biomedical diagnostic applications, which directly utilizes the scattering patterns to reconstruct the deep and non-line-of-sight objects. However, the course of the translation of this technique to preclinical biomedical imaging applications has been postponed by the following two facts: 1) the field of view of SCOSI was significantly limited by the optical memory effect, and 2) the molecular-tagged functional imaging of the biological tissues remains largely unexplored. In this work, a proof-of-concept design of the first-generation widefield functional SCOSI (WF-SCOSI) system was presented for simultaneously achieving mesoscopic mapping of fluid morphology and flow rate, which was realized by implementing the concepts of scanning synthesis and fluorescence scattering flowmetry. The ex vivo imaging results of the fluorescence-labeled large-scale blood vessel network phantom underneath the strong scatters demonstrated the effectiveness of WF-SCOSI toward non-invasive hemodynamic imaging applications.


Asunto(s)
Diagnóstico por Imagen , Hemodinámica , Fantasmas de Imagen , Reología , Diseño de Equipo , Imagen Óptica/métodos
4.
Opt Lett ; 49(11): 3102-3105, 2024 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-38824338

RESUMEN

In this Letter, a novel, to the best of our knowledge, vertical directional coupling waveguide grating (VDCWG) architecture is proposed to increase the length of waveguide grating antennas for large aperture on-chip optical phased arrays (OPAs). In this new architecture, the grating emission strength is engineered by the vertical directional coupler, which provides additional degrees of design freedom. Theoretical analysis and numerical simulation show that the VDCWG can adjust the grating strength in the range of more than two orders of magnitude, corresponding to an effective grating length more than a centimeter. For proof-of-concept, a VDCWG antenna with a length of 1.5 mm is experimentally demonstrated. The grating strength is measured to be 0.17 mm-1, and the far-field divergence angle is 0.061°. A 16-channel OPA is also developed based on the proposed VDCWG, which proves the potential of the new architecture for large aperture OPAs.

5.
Opt Lett ; 49(7): 1725-1728, 2024 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-38560847

RESUMEN

Ultrasound coupling is one of the critical challenges for traditional photoacoustic (or optoacoustic) microscopy (PAM) techniques transferred to the clinical examination of chronic wounds and open tissues. A promising alternative potential solution for breaking the limitation of ultrasound coupling in PAM is photoacoustic remote sensing (PARS), which implements all-optical non-interferometric photoacoustic measurements. Functional imaging of PARS microscopy was demonstrated from the aspects of histopathology and oxygen metabolism, while its performance in hemodynamic quantification remains unexplored. In this Letter, we present an all-optical thermal-tagging flowmetry approach for PARS microscopy and demonstrate it with comprehensive mathematical modeling and ex vivo and in vivo experimental validations. Experimental results demonstrated that the detectable range of the blood flow rate was from 0 to 12 mm/s with a high accuracy (measurement error:±1.2%) at 10-kHz laser pulse repetition rate. The proposed all-optical thermal-tagging flowmetry offers an effective alternative approach for PARS microscopy realizing non-contact dye-free hemodynamic imaging.


Asunto(s)
Técnicas Fotoacústicas , Tecnología de Sensores Remotos , Técnicas Fotoacústicas/métodos , Reología/métodos , Ultrasonografía/métodos , Microscopía/métodos
6.
Opt Express ; 31(15): 24110-24126, 2023 Jul 17.
Artículo en Inglés | MEDLINE | ID: mdl-37475246

RESUMEN

We investigate the power scaling and thermal management of multi-point side-pumped 2.825 µm heavily-erbium-doped fluoride fiber lasers by numerical simulation. The 4-point (or 6-point) erbium-doped fluoride fiber laser with polished erbium-doped fluoride fiber-based side-pump couplers delivers an output laser power of over 100 W at each launched 981 nm pump power of 100 W (or 75 W). Meanwhile, the core temperature increases of the gain fiber tips are below 1 K, making it possible for a highly reflective fiber Bragg grating to work stably in high-power operation. Once the preparation processes of these erbium-doped fluoride fiber-based side-pump couplers and endcaps with effective coatings are mature, the proposed multi-point side-pumped erbium-doped fluoride fiber lasers with some feasibility may theoretically pave the way for the development of hundred-watt mid-infrared fiber lasers with effective thermal management.

7.
Opt Express ; 31(15): 25177-25190, 2023 Jul 17.
Artículo en Inglés | MEDLINE | ID: mdl-37475329

RESUMEN

This work theoretically investigates the relative intensity noise (RIN) and spectral linewidth characteristics of epitaxial quantum dot (QD) lasers on silicon subject to optical injection. The results show that the RIN of QD lasers can be reduced by optical injection, hence a reduction of 10 dB is achieved which leads to a RIN as low as -167.5 dB/Hz in the stable injection-locked area. Furthermore, the spectral linewidth of the QD laser can be greatly improved through the optical injection locked scheme. It is reduced from 556.5 kHz to 9 kHz with injection ratio of -60 dB and can be further reduced down to 1.5 Hz with injection ratio of 0 dB. This work provides an effective method for designing low intensity noise and ultra-narrow linewidth QD laser sources for photonics integrated circuits on silicon.

8.
Opt Lett ; 48(21): 5627-5630, 2023 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-37910719

RESUMEN

Photoacoustic microscope (PAM) with a low-optical NA suffers from a limited view along the optical axis, due to the coherent cancellation of acoustic pressure waves after being excited with a smoothly focused beam. Using larger-NA (NA > 0.3) objectives can readily overcome the limited-view problem, while the consequences are the shallow working distance and time-consuming depth scanning for large-volume imaging. Instead, we report an off-axis oblique detection strategy that is compatible with a low-optical-NA PAM for turning up the optical-axis structures. Comprehensive photoacoustic modeling and ex vivo phantom and in vivo mouse brain imaging experiments are conducted to validate the efficacy of correcting the limited view. Proof-of-concept experiment results show that the visibility of optical-axis structures can be greatly enhanced by making the detection angle off the optical axis larger than 45°, strongly recommending that off-axis oblique detection is a simple and cost-effective alternative method to solve the limited-view problems in low-optical-NA PAMs.

9.
Opt Express ; 30(7): 10732-10742, 2022 Mar 28.
Artículo en Inglés | MEDLINE | ID: mdl-35473033

RESUMEN

Relying on the nonlinear multimode interference in multimode fibers and the nonlinear polarization rotation, these two mode-locked techniques are combined in our proposed fiber laser. Stable optical soliton and multi-pulse regimes with a constant frequency of 11.44 MHz have been generated experimentally. Through altering intra-cavity conditions, bound-state pulses with diverse properties are observed. To the best of our knowledge, the obtained bound-state pulse constituted by more than thirty sub-pulses is achieved for the first time. Moreover, the center wavelength of bound-state pulse could be switched in a certain range covering the entire C band.

10.
Opt Lett ; 47(20): 5397-5400, 2022 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-36240373

RESUMEN

Waveguide grating antenna (WGA) is a key component for an on-chip optical phased array. In order to form a beam with a small divergence angle, WGAs of several millimeters in length are highly desired. However, in high-index-contrast platforms such as silicon-on-insulator (SOI), such long WGAs typically require weakly modulated gratings with critical feature sizes below 10 nm. In this paper, we experimentally demonstrate a new, to the best of our knowledge, strategy to implement long WGAs. Instead of directly modulating a waveguide, we propose periodically modulating the evanescent field with subwavelength blocks. With this arrangement, weak grating strength can be achieved while maintaining a minimum feature size as large as 100 nm. For proof-of-concept, we experimentally demonstrate a 1-mm-long, single-etched WGA on a conventional 220 nm SOI platform, which achieves a far-field divergence angle of 0.095° and a wavelength scanning sensitivity of 0.168°/nm.

11.
Opt Express ; 29(10): 15133-15144, 2021 May 10.
Artículo en Inglés | MEDLINE | ID: mdl-33985219

RESUMEN

Because of the high index contrast, current silicon photonics based optical phased arrays cannot achieve small beam divergence and large field-of-view simultaneously without increasing fabrication complexity. To resolve the dilemma, we propose an ultra-long waveguide grating antenna formed by placing subwavelength segments within the evanescent field of a conventional strip waveguide. Bound state in the continuum effect is leveraged to suppress the sidewall emission. As a proof of concept, we theoretically demonstrated a millimeter-long through-etched waveguide grating antenna with a divergence angle of 0.081° and a feature size compatible with current silicon photonics foundries.

12.
Opt Lett ; 46(19): 5000-5003, 2021 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-34598252

RESUMEN

We experimentally demonstrate an ultra-compact polarization-independent 3 dB power splitter on the silicon-on-insulator platform. Subwavelength structure engineering is employed to balance the coupling coefficients of TE and TM polarizations as well as a footprint reduction. The device possesses ultra-compact (1.2µm×2.62µm) and polarization-independent features with an operating bandwidth over 50 nm (from 1540 to 1590 nm).

13.
Cells Tissues Organs ; 210(1): 10-23, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33910192

RESUMEN

The basement membrane interacts directly with the vocal fold epithelium. Signaling between the basement membrane and the epithelium modulates gene regulation, differentiation, and proliferation. The purpose of this study was to identify an appropriate simple single-protein substrate for growth of rabbit vocal fold epithelial cells. Vocal folds from 3 New Zealand white rabbits (Oryctolagus cuniculus) were treated to isolate epithelial cells, and cells were seeded onto cell culture inserts coated with collagen I, collagen IV, laminin, or fibronectin. Transepithelial electrical resistance (TEER) was measured, and phase contrast microscopy, PanCK, CK14, and E-cadherin immunofluorescence were utilized to assess for epithelial cell-type characteristics. Further investigation via immunofluorescence labeling was conducted to assess proliferation (Ki67) and differentiation (Vimentin). There was a significant main effect of substrate on TEER, with collagen IV eliciting the highest, and laminin the lowest resistance. Assessment of relative TEER across cell lines identified a larger range of TEER in collagen I and laminin. Phase contrast imaging identified altered morphology in the laminin condition, but cell layer depth did not appear to be related to TEER, differentiation, or morphology. Ki67 staining additionally showed no significant difference in proliferation. All conditions had confluent epithelial cells and dispersed mesenchymal cells, with increased mesenchymal cell numbers over time; however, a higher proportion of mesenchymal cells was observed in the laminin condition. The results suggest collagen IV is a preferable basement membrane substrate for in vitro vocal fold epithelial primary cell culture, providing consistent TEER and characteristic cell morphology, and that laminin is an unsuitable substrate for vocal fold epithelial cells and may promote mesenchymal cell proliferation.


Asunto(s)
Células Epiteliales , Pliegues Vocales , Animales , Membrana Basal , Adhesión Celular , Recuento de Células , Células Cultivadas , Colágeno Tipo IV , Laminina , Conejos
14.
Appl Opt ; 60(13): 3641-3646, 2021 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-33983296

RESUMEN

A $Q$-switched mode-locked square noise-like pulse (QMLSNLP) is generated in a nonlinear polarization rotation passively mode-locked fiber laser. When the pump power changes from 154 mW to 414 mW, the frequency of the $Q$-switched envelope varies from 21.7 kHz to 38.9 kHz, while the duration of the $Q$-switched envelope decreases from $5.1\,\,{\unicode{x00B5}\rm s}$ to $3.2{\unicode{x00B5}\rm s}$, correspondingly. In the meantime, QMLSNLP keeps the fundamental repetition rate constant, and the pulse duration increases from 3.4 ns to 6.7 ns. By inserting different lengths of single-mode fiber into the ring cavity, the evolutions of QMLSNLP are measured and analyzed. According to the cavity parameters and experimental results, impacts of the cavity length on QMLSNLP are investigated in detail.

15.
Appl Opt ; 59(24): 7396-7407, 2020 Aug 20.
Artículo en Inglés | MEDLINE | ID: mdl-32902508

RESUMEN

The orbital angular moment (OAM) of light has been proved to be useful in plenty of applications. By transmitting the OAM of the focused light field to a particle, it will be orbited around the optical axis. Therefore, it is necessary to study the OAM distribution of the focused light field used to manipulate the particles. In this application, the widely used paraxial approximation is no longer sufficient due to the tightly focused beam. We employ the higher-order Poincaré sphere to represent the Laguerre-Gaussian (LG) beams with arbitrary polarization. Then the Rayleigh-Sommerfeld integral method and the q-parameter method are used to derive the analytical expression of the light field on the focal plane. Based on this, the OAM density expression of the tightly focused LG beam is derived. In the numerical simulation, we study and analyze the unique intensity distributions and OAM distributions of tightly focused linear polarized, radial polarized, and circular polarized LG beams. The results could be leveraged to further explore the applications of the polarized vortex beam.

16.
Phys Rev Lett ; 122(15): 155901, 2019 Apr 19.
Artículo en Inglés | MEDLINE | ID: mdl-31050539

RESUMEN

Because of their weak interlayer bonding, van der Waals (vdW) solids are very sensitive to external stimuli such as strain. Experimental studies of strain tuning of thermal properties in vdW solids have not yet been reported. Under ∼9% cross-plane compressive strain created by hydrostatic pressure in a diamond anvil cell, we observed an increase of cross-plane thermal conductivity in bulk MoS_{2} from 3.5 to about 25 W m^{-1} K^{-1}, measured with a picosecond transient thermoreflectance technique. First-principles calculations and coherent phonon spectroscopy experiments reveal that this drastic change arises from the strain-enhanced interlayer interaction, heavily modified phonon dispersions, and decrease in phonon lifetimes due to the unbundling effect along the cross-plane direction. The contribution from the change of electronic thermal conductivity is negligible. Our results suggest possible parallel tuning of structural, thermal, and electrical properties of vdW solids with strain in multiphysics devices.

17.
Opt Express ; 25(2): 595-604, 2017 Jan 23.
Artículo en Inglés | MEDLINE | ID: mdl-28157949

RESUMEN

In this paper, the peak-to-average power ratio (PAPR) reduction problem with tone injection (TI) in the direct current-biased optical orthogonal frequency division multiplexing (DCO-OFDM) system is investigated, which is formulated as a tough integer combinatorial optimization problem. Since it is a challenging task to find the global optimal solution, the branch-and-bound method (BBM), which is extensively employed to deal with the NP-hard problem, is introduced to solve this problem. By splitting the superior branches and pruning the inferior branches, the close optimal solution is obtained. Simulation results reveal that the proposed BBM-based TI method has superior PAPR reduction and bit error rate (BER) performance compared with some existing algorithms. The proposed algorithm ensures a relatively low peak value, and thus provides an important benchmark in performance evaluations relative to other existing algorithms targeting at the same problem.

18.
Opt Express ; 25(20): 24448-24458, 2017 Oct 02.
Artículo en Inglés | MEDLINE | ID: mdl-29041389

RESUMEN

The dc-biased optical orthogonal frequency division multiplexing (DCO-OFDM) system is experimentally demonstrated as an appealing candidate in future visible light communication (VLC) system. However, the intrinsic high PAPR drawback that the DCO-OFDM system suffers from still needs to be addressed and few effective approach has been found so far. To deal with this problem, in this paper, the tone reservation (TR) technique based the time domain kernel matrix (TKM-TR) schemes for reducing the PAPR are studied and applied to DCO-OFDM system. Aiming at the drawback of its severe tailing in previous TKM-TR schemes, first an improved TKM-TR scheme is proposed, in which the peak regrowth caused by severe tailing is eliminated by optimizing the scaling factors. In addition, considering the clipping ratio (CR) value in TKM-TR scheme is greatly related to the PAPR reduction performance, an extensively used heuristic global optimization algorithm, the particle swarm optimization (PSO) method is employed in TKM-TR to obtain a better CR for more PAPR reduction. Simulation results show that the improved TKM-TR scheme can efficiently address the tailing problem in previous TKM-TR schemes and achieve better PAPR reduction. Moreover, due to the powerful searching ability, PSO based TKM-TR scheme achieves more PAPR reduction and lower bit error rate (BER).

19.
Opt Express ; 25(9): 10527-10535, 2017 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-28468425

RESUMEN

Compared to the conventional strip waveguide microring resonators, subwavelength grating (SWG) waveguide microring resonators have better sensitivity and lower detection limit due to the enhanced photon-analyte interaction. As sensors, especially biosensors, are usually used in absorptive ambient environment, it is very challenging to further improve the detection limit of the SWG ring resonator by simply increasing the sensitivity. The high sensitivity resulted from larger mode-analyte overlap also brings significant absorption loss, which deteriorates the quality factor of the resonator. To explore the potential of the SWG ring resonator, we theoretically and experimentally optimize an ultrasensitive transverse magnetic mode SWG racetrack resonator to obtain maximum quality factor and thus lowest detection limit. A quality factor of 9800 around 1550 nm and sensitivity of 429.7 ± 0.4nm/RIU in water environment are achieved. It corresponds to a detection limit (λ/S·Q) of 3.71 × 10-4 RIU, which marks a reduction of 32.5% compared to the best value reported for SWG microring sensors.

20.
Opt Express ; 24(26): 29724-29733, 2016 Dec 26.
Artículo en Inglés | MEDLINE | ID: mdl-28059356

RESUMEN

In this paper, unique surface sensing property and enhanced sensitivity in microring resonator biosensors based on subwavelength grating (SWG) waveguides are studied and demonstrated. The SWG structure consists of periodic silicon pillars in the propagation direction with a subwavelength period. Effective sensing region in the SWG microring resonator includes not only the top and side of the waveguide, but also the space between the silicon pillars on the light propagation path. It leads to greatly increased sensitivity and a unique surface sensing property in contrast to common evanescent wave sensors: the surface sensitivity remains constantly high as the surface layer thickness grows. Microring resonator biosensors based on both SWG waveguides and conventional strip waveguides were compared side by side in surface sensing experiment and the enhanced surface sensing capability in SWG based microring resonator biosensors was demonstrated.

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