Accelerated Fatigue Test for Electric Vehicle Reducer Based on the SVR-FDS Method.

The reducer serves as a pivotal component within the power transmission system of electric vehicles. On one hand, it bears the torque load within the power transmission system. On the other hand, it also endures the vibration load transmitted from other vehicle components. Over extended periods, these dynamic loads can cause fatigue damage to the reducer. Therefore, the reliability and durability of the reducer during use are very important for electric vehicles. In order to save time and economic costs, the durability of the reducer is often evaluated through accelerated fatigue testing. However, traditional approaches to accelerated fatigue tests typically only consider the time-domain characteristics of the load, which limits precision and reliability. In this study, an accelerated fatigue test method for electric vehicle reducers based on the SVR-FDS method is proposed to enhance the testing process and ensure the reliability of the results. By utilizing the support vector regression (SVR) model in conjunction with the fatigue damage spectrum (FDS) approach, this method offers a more accurate and efficient way to evaluate the durability of reducers. It has been proved that this method significantly reduces the testing period while maintaining the necessary level of test reliability. The accelerated fatigue test based on the SVR-FDS method represents a valuable approach for assessing the durability of electric vehicle reducers and offering insights into their long-term performance.

Sensor-Enhanced Thick Laminated Composite Beams: Manufacturing, Testing, and Numerical Analysis.

This study investigates the manufacturing, testing, and analysis of ultra-thick laminated polymer matrix composite (PMC) beams with the aim of developing high-performance PMC leaf springs for automotive applications. An innovative aspect of this study is the integration of Fiber Bragg Grating (FBG) sensors and thermocouples (TCs) to monitor residual strain and exothermic reactions in composite structures during curing and post-curing manufacturing cycles. Additionally, the Calibration Coefficients (CCs) are calculated using Strain Gauge measurement results under static three-point bending tests. A major part of the study focuses on developing a properly correlated Finite Element (FE) model with large deflection (LD) effects using geometrical nonlinear analysis (GNA) to understand the deformation behavior of ultra thick composite beam (ComBeam) samples, advancing the understanding of large deformation behavior and filling critical research gaps in composite materials. This model will help assess the internal strain distribution, which is verified by correlating data from FBG sensors, Strain Gauges (SGs), and FE analysis. In addition, this research focuses on the application of FBG sensors in structural health monitoring (SHM) in fatigue tests under three-point bending with the support of load-deflection sensors: a new approach for composites at this scale. This study revealed that the fatigue performance of ComBeam samples drastically decreased with increasing displacement ranges, even at the same maximum level, underscoring the potential of FBG sensors to enhance SHM capabilities linked to smart maintenance.

Effects of Long Term Fatigue Cycling on In Situ Fenestrations of Polyethylene Terephthalate and Expanded Polytetrafluorethylene Thoracic Aortic Stent grafts: An Experimental Study.

OBJECTIVE: In this study, the long term durability of fenestrations after in situ fenestration (ISF) of five commercial thoracic aortic stent grafts was evaluated in an in vitro experiment after a simulated 10 year period. METHODS: Five different thoracic aortic stent grafts (Relay, Valiant, Hercules, TAG, and Ankura, with a diameter of 34 mm) received both needle and laser ISF in vitro. A Viabahn (11 × 50 mm) was released in each fenestration as a bridging stent graft. Long term fatigue tests (simulating 10 years) of each of the fenestrated stent grafts were then conducted in a flow fatigue test system. The area, shape, margin, and the long and short axis of all the fenestrations were evaluated with light microscopy before and after the fatigue test. The leakage from the fenestration junction before and after the long term fatigue was also measured. RESULTS: The experimental results showed no obvious difference between needle and laser fenestrations. The long axes of all the fenestrations remained unchanged, while the short axes increased after the fatigue test, which was significant in Relay, Valiant, and Hercules polyethylene terephthalate stent grafts. The shape scores of fenestrations improved after the fatigue test in Valiant and Hercules, remained unchanged in Relay and Ankura, and worsened in the TAG. After the fatigue cycling, the average leakage from the fenestration junction decreased in all the stent grafts, and the Ankura had the maximum decline rate. CONCLUSION: The ISF technique was durable over a simulated 10 year period. The fenestrations were positively remodelled to be more circular, and the leakage from the junction decreased after long term fatigue testing.

Device for Torsional Fatigue Strength Assessment Adapted for Pulsating Testing Machines.

The torsional fatigue test determines the fatigue limit for a certain asymmetry coefficient of the cycle. The assessment of fatigue tests is performed on specialized machines. There are two types of torsion testing machines: universal machines that have the torsion component and specialized machines only for torsion testing. Nevertheless, no matter which proposed option we choose, the purchase prices for these testing machines or the values spent for self-management are quite high. This paper presented a device used for torsion fatigue testing, adaptable to a universal pulsating testing machine, designed to determine the torsion fatigue limit for different materials. The built device is simple and reliable, and therefore inexpensive. By using this device, we can determine the limit of the torsional fatigue after any stress cycle and we can use the parameters obtained from the universal machine to which it was attached. The torque and twisting angle of the test specimen during the test can be determined by calculation. The paper also presented an experimental method for determining shear strains based on calibration experiment, using a specimen on which strain gauges were mounted. The values taken from this calibration experiment were compared with those obtained from the theoretical calculation.

Fatigue Crack Propagation Estimation Based on Direct Strain Measurement during a Full-Scale Fatigue Test.

Military aircraft are subjected to variable loads, which are the main cause of initiation and propagation of cracks in the most stressed locations of the airframe. The aim of a Full-Scale Fatigue Test (FSFT) is to represent actual load conditions in such a way that the results obtained are a good representation of the actual loads and may be used as data that give insight into the development of real fatigue damage in critical locations. The FSFT load spectrum is a generalized depiction of the expected service loads and is designed to give an overall good representation of loads exerted on the airframe's structural elements during operation. Moreover, the discrete method of load application on the structure (exerting loads with hydraulic actuators rather than pressure fields or inertia loads expected in actual operation) may cause some local effects, which may not be present in operation. The proposed usage of direct strain data from the test include such local effects. Moreover, operational loads may vary between individual aircraft, therefore it is crucial to understand the whole process of fatigue crack onset and development in order to determine safe inspection intervals and thereby mitigate risk. This paper presents crack propagation calculations regarding the development of a crack in a critical location of the PZL-130 "Orlik" TC-II aircraft, discovered during FSFT. The discussed crack was found already developed, hence the information about nucleation and initial propagation of the crack was not available. Therefore, there was a need to recreate the whole propagation process by means of numerical estimations using the FSFT results like location of the crack and total life for model validation. Moreover, in order to gather real load data for calculations a dedicated stain gage was installed on the damaged load path to monitor the actual remote strain in the element during the FSFT. This allowed for the definition of load sequence exerted on the damaged element directly during the test rather than estimating it from the general load conditions of the wing. The calculations allowed for the estimation of crack propagation curves from initiation to critical crack length causing fatal damage. The obtained curves allowed to visualize the crack behavior due to applied load and furthermore define initial and recurring inspection intervals for the entire fleet during operation, which allowed to define which cracks could be found before they reach critical size in order to carry out mitigation actions like repair or replacement of the damaged part. The authors present the methodology for load spectrum development based on direct strain measurements and furthermore crack propagation curves estimation, validated with the actual FSFT results, which allowed to propose nondestructive inspection intervals for future operation.

Mechanical Study of Various Pedicle Screw Systems including Percutaneous Pedicle Screw in Trauma Treatment.

Background and Objectives: Spine surgery using a percutaneous pedicle screw placement (PPSP) is widely implemented for spinal trauma. However, percutaneous systems have been reported to have weak screw-rod connections. In this study, conventional open and percutaneous systems were biomechanically evaluated and compared. Material and Methods: The experiments were performed in two stages: the first stage was a break test, whereas the second stage was a fatigue test. Four systems were used for the experiments. System 1 was intended for conventional open surgery (titanium rod with a 6.0 mm diameter, using a clamp connecting mechanism). System 2 was a percutaneous pedicle screw (PPS) system for trauma (titanium alloy rod with a 6.0 mm diameter, using ball ring connections). System 3 was a PPS system for trauma (cobalt-chromium alloy rod with a 6.0 mm diameter, using sagittal adjusting screw connections). System 4 was a general-purpose PPS system (titanium alloy rod with a 5.5 mm diameter, using a mechanism where the adapter in the head holds down the screw). Results: Stiffness values of 54.8 N/mm, 43.1 N/mm, 90.9 N/mm, and 39.3 N/mm were reported for systems 1, 2, 3, and 4, respectively. The average number of load cycles in the fatigue test was 134,393, 40,980, 1,550,389, and 147,724 for systems 1 to 4, respectively. At the end of the test, the displacements were 0.2 mm, 16.9 mm, 1.2 mm, and 8.6 mm, respectively. System 1, with a locking mechanism, showed the least displacement at the end of the test. Conclusion: A few PPS systems showed better results in terms on stiffness and life than the open system. The experiments showed that mechanical strength varies depending on the spinal implant. The experiments conducted are essential and significant to provide the mechanical strength required for surgical reconstruction.

Fatigue Resistance of the Advanta V12/iCast and Viabahn Balloon-Expandable Stent-Graft as Bridging Stents in Experimental Fenestrated Endografting.

PURPOSE: Bridging stents undergo millions of cycles during respiratory movements of the kidneys throughout the patient's life. Thus, understanding the response of fabric and endoskeleton of the stent to cyclic loading over the time is crucial. In this study, we compare the fatigue resistance of the Viabahn Balloon-Expandable stent-graft (VBX) with the widely used Advanta V12/iCast under prolonged stress induction. MATERIALS AND METHODS: A polyester test sheet with 10 fenestrations was used simulating a fenestrated endograft. Five 6×59 mm VBX stent-grafts and five 6×58 mm Advanta stent-grafts were implanted into 6×6 mm fenestrations. The stents were flared with a 10×20 mm PTA (percutaneous transluminal angioplasty) catheter and connected with a fatigue stress machine. All stent-grafts were evaluated by microscopy and radiography at baseline and after regular intervals until 50,000,000 cycles were applied, simulating a life span of approximately 75 months. Freedom from fracture (FF), freedom from initial polytertafluoroethylene (PTFE) changes (FIC), and from PTFE breakpoint (FBP, all-layer defect) were calculated. RESULTS: Digital radiographic images did not show any stent fracture in both groups after 50,000,000 cycles. The VBX stent-graft was free from any all-layer defects at the conclusion of 50,000,00 cycles resulting in a significant higher FBP compared with Advanta V12 (50,000,000 vs 33,400,000; p<0.01). All-layer defects were observed only in the Advanta group. Two of 5 Advanta stents showed early penetration of the nitinol ring causing a defect of PTFE. Regarding FIC, there was no significant difference between the stents (3,400,000 in VBX vs 3,200,000 in Advanta). CONCLUSIONS: In fatigue tests simulating respiration movements, VBX and Advanta V12 performed equally well in terms of fracture resistance and freedom from initial PTFE changes. VBX maintained freedom from PTFE breakpoint throughout the full 50,000,000 cycles. All-layers defects were detected only in Advanta and were mainly caused by penetration of the nitinol ring through the PTFE.

Vibration Fatigue Damage Estimation by New Stress Correction Based on Kurtosis Control of Random Excitation Loadings.

In the pioneer CAE stage, life assessment is the essential part to make the product meet the life requirement. Commonly, the lives of flexible structures are determined by vibration fatigue which accrues at or close to their natural frequencies. However, existing PSD vibration fatigue damage estimation methods have two prerequisites for use: the behavior of the mechanical system must be linear and the probability density function of the response stresses must follow a Gaussian distribution. Under operating conditions, non-Gaussian signals are often recorded as excitation (usually observed through kurtosis), which will result in non-Gaussian response stresses. A new correction is needed to make the PSD approach available for the non-Gaussian vibration to deal with the inevitable extreme value of high kurtosis. This work aims to solve the vibration fatigue estimation under the non-Gaussian vibration; the key is the probability density function of response stress. This work researches the importance of non-Gaussianity numerically and experimentally. The beam specimens with two notches were used in this research. All excitation stays in the frequency range that only affects the second natural frequency, although their kurtosis is different. The results show that the probability density function of response stress under different kurtoses can be obtained by kurtosis correction based on the PSD approach of the frequency domain.

The Experimental Verification of Direct-Write Silver Conductive Grid and ARIMA Time Series Analysis for Crack Propagation.

The paper presents experimental verification of customized resistive crack propagation sensors as an alternative method for other common structural health monitoring (SHM) techniques. Most of these are sensitive to changes in the sensor network configuration and a baseline dataset must be collected for the analysis of the structure condition. Sensors investigated within the paper are manufactured by the direct-write process with electrically conductive, silver-microparticle-filled paint to prepare a tailored measuring grid on an epoxy or polyurethane coating as a driving/insulating layer. This method is designed to enhance the functionality and usability compared to commercially available crack gauges. By using paint with conductive metal particles, the shape of the sensor measuring grid can be more easily adapted to the structure, while, in the previous approach, only a few grid-fixed sensors are available. A fatigue test on the compact tension (CT) specimen is presented and discussed to evaluate the ability of the developed sensors to detect and monitor fatigue cracks. Additionally, the ARIMA time series algorithm is developed both for monitoring and predicting crack growth, based on the acquired data. The proposed sensors' verification reveal their good performance to detect and monitor fatigue fractures with a relatively low measurement error and ARIMA estimated crack length compared with the crack opening displacement (COD) gauge.

[Research Method of Fatigue Performance of Surgically Implanted Heart Valve Stent].

The aim of this study was to evaluate the fatigue property in vitro of a domestic surgically implanted heart valve stent (SIHVS). The domestic SIHVS was used as a testing sample, and a protocol was developed according to the standards GB 12279-2008 and ISO 5840-2:2015. A dynamic fatigue testing machine was used to apply for a 0.365 mm cyclic radial displacement at the end of the SIHVS. The SIHVS were observed after 400 million cycles by a scanning electron microscope. The observed results show that the structure of SIHVS is intact. There are no fracture, no obvious wear, and no loosening of the wire and casing. In the tested stents, no structural distortion, no cracks and obvious pits were observed. This study demonstrated that SIHVS structure meets the expected fatigue performance requirements.

Validation and Improvement of a Bicycle Crank Arm Based in Numerical Simulation and Uncertainty Quantification.

In this study, a finite element model of a bicycle crank arm are compared to experimental results. The structural integrity of the crank arm was analyzed in a universal dynamic test bench. The instrumentation used has allowed us to know the fatigue behavior of the component tested. For this, the prototype was instrumented with three rectangular strain gauge rosettes bonded in areas where failure was expected. With the measurements made by strain gauges and the forces registers from the load cell used, it has been possible to determine the state of the stresses for different loads and boundary conditions, which has subsequently been compared with a finite element model. The simulations show a good agreement with the experimental results, when the potential sources of uncertainties are considered in the validation process. This analysis allowed us to improve the original design, reducing its weight by 15%. The study allows us to identify the manufacturing process that requires the best metrological control to avoid premature crank failure. Finally, the numerical fatigue analysis carried out allows us to conclude that the new crank arm can satisfy the structural performance demanded by the international bicycle standard. Additionally, it can be suggested to the standard to include the verification that no permanent deformations have occurred in the crank arm during the fatigue test. It has been observed that, in some cases this bicycle component fulfils the minimum safety requirements, but presents areas with plastic strains, which if not taken into account can increase the risk of injury for the cyclist due to unexpected failure of the component.

Differentiation of the Strength of Back Muscle Contraction Under Fatigue: Does Force Feedback Play a Role?

OBJECTIVE: This study investigates the ability of subjects to differentiate the strength of back muscle contraction with and without feedback information on force produced under fatigue and nonfatigue conditions. DESIGN: Controlled laboratory study. SETTING: Research laboratory environment. PARTICIPANTS: A group of 52 healthy young men participated in the study. INTERVENTION: Subjects self-estimated 50% of the maximal voluntary isometric contraction of back muscles either on their own volition or on the basis of information about the actual force, before and after the Sørensen fatigue test. MAIN OUTCOME MEASURES: The force was measured by means of the FiTRO Back Dynamometer. RESULTS: The self-estimated 50% maximal voluntary isometric contraction was significantly higher than the one calculated from maximal voluntary isometric contraction during 10 trials in 2 repeated sessions (8.3% and 10.0%, P < .05). However, when feedback on the force produced was provided, significantly higher values were observed during an initial trial in both sessions (8.5%, P = .04 and 12.1%, P = .01). Subjects were able to estimate the target force during the following trials. Fatigue induced a decrease in peak force (7.7%, P = .04), whereas the ability to regulate the prescribed force was not compromised. Constant error was lower with than without force feedback during both measurements (2.15% and 6.85%; 3.06% and 8.56%). However, constant and variable errors were greater under fatigue than nonfatigue conditions (8.43% and 5.55%; 0.41% and 0.37%). Similarly, root mean square error decreased with force feedback (from 6.88% to 3.48% and from 8.74% to 5.09%) and increased under fatigue (from 5.87% to 8.67%). CONCLUSIONS: These findings indicate that force feedback plays a role in the differentiation of the strength of back muscle contraction, regardless of fatigue. It contributes to a more precise regulation of force produced during voluntary isometric contraction of back muscles. This promising method awaits further experimentation to be applied for individuals with low back pain.

Use of a simple in vitro fatigue test to assess materials used in the surgical treatment of stress urinary incontinence and pelvic organ prolapse.

AIMS: Stress urinary incontinence and pelvic organ prolapse are very common conditions with a proportion of patients requiring implantation of synthetic materials for a durable repair. However increasing numbers of post-surgical complications have been reported related to the use of polypropylene meshes. One hypothesis for the adverse response is poor mechanical matching of the relatively stiff polypropylene mesh particularly as materials in the pelvic floor will need to cope with decades of distension as occurs with increase of intraabdominal pressure on coughing, laughing, or sneezing. METHODS: In this study we have undertaken a very simple fatigue testing regime to compare the mechanical abilities of six materials. Four commercial meshes in clinical use and two novel electrospun materials not yet evaluated in the clinic were assessed using a uniaxial tensile test. This was performed on six samples of each dry material and on another six samples of each material after just 3 days of fatigue conditions using a dynamic bioreactor. RESULTS: The four commercial materials showed permanent mechanical deformation after just 3 days of stretching these materials by 25% elongation on a regular dynamic cycle, whereas the two new materials presented more elastic properties without deformation. CONCLUSIONS: We suggest that a test as simple as this 3-day fatigue testing is sufficient to distinguish between materials which have already been found to cause complications clinically and newer materials yet to be tested clinically which will hopefully prove more mechanically appropriate for implantation in the pelvic floor.

Fatigue Performance of Type I Fibre Bragg Grating Strain Sensors.

Although fibre Bragg gratings (FBGs) offer obvious potential for use in high-density, high-strain sensing applications, the adoption of this technology in the historically conservative aerospace industry has been slow. There are several contributing factors, one of which is variability in the reported performance of these sensors in harsh and fatigue prone environments. This paper reports on a comparative evaluation of the fatigue performance of FBG sensors written according to the same specifications using three different grating manufacturing processes: sensors written in stripped and re-coated fibres, sensors written during the fibre draw process and sensors written through fibre coating. Fatigue cycling of the fibres is provided by a customized electro-dynamically actuated loading assembly designed to provide high frequency and amplitude loading. Pre- and post-fatigue microscopic analysis and high-resolution transmission and reflection spectra scanning are conducted to investigate the fatigue performance of FBGs, the failure regions of fibres as well as any fatigue-related effects on the spectral profiles. It was found that because of the unique fabrication method, the sensors written through the fibre coating, also known as trans-jacket FBGs, show better fatigue performance than stripped and re-coated FBGs with greater control possible to tailor the optical reflection properties compared to gratings written in the draw tower. This emerging method for inscription of Type I gratings opens up the potential for mass production of higher reflectivity, apodised sensors with dense or complex array architectures which can be adopted as sensors for harsh environments such as in defence and aerospace industries.

Mechanical Behaviors and Fatigue Performances of Ballastless Tracks Laid on Long-Span Cable-Stayed Bridges with Different Arrangements.

In this paper, we present a new attempt to lay ballastless tracks on long-span cable-stayed bridges on high-speed railways. The arrangements of ballastless tracks laid on cable-stayed bridges can be divided into two conditions: (i) across the cable suspension-point cross-section or (ii) in discontinuity at the cable suspension-point cross-section. At present, there is a lack of in-depth research on ballastless tracks laid on long-span cable-stayed bridges, especially on the mechanical behaviors and fatigue performances of the ballastless tracks with different arrangements. For this paper, a segmental model of a long-span cable-stayed bridge was designed and built, on which full-scale ballastless tracks with two different arrangements were arranged. A series of fatigue tests and post-fatigue loading tests were carried out based on the two selected full-scale ballastless tracks. Some conclusions were drawn as follows. For the longitudinal end of the ballastless track, which is far from the loading positions, the interlayers of the ballastless tracks tend to warp up relatively, and the compressive pressures at the interlayers are also unloaded. However, there is no void or gap formed at the interlayers of the longitudinal end of the track slab due to the precompression of the rubber isolation layer. For the center of the track slab, which is close to the loading positions, the compressive deformations occur at the interlayers, and the pressures at interlayers are also increased. The maximum compressive deformation is less than 0.5 mm under the standard train axle load (170 kN), and it cannot affect the high-speed trains' operation. With the increase of the post-fatigue loading, the load-displacement curves and the load-pressure variation curves of the ballastless tracks show apparent nonlinearity. Moreover, with the increase of the fatigue loading cycles, the compressive stiffness enhancement or degradation of the ballastless tracks are not noticeable. That is to say, the ballastless tracks laid on the long-span cable-stayed bridges with different arrangements have good mechanical behaviors, and their fatigue performances can also be guaranteed after bearing repeated loadings.

Hamstring-to-quadriceps fatigue ratio offers new and different muscle function information than the conventional non-fatigued ratio.

Commonly used injury risk prediction tests such as the hamstring-to-quadriceps (H:Q) strength ratio appear to be poor predictors of non-contact injury. However, these tests are typically performed in a non-fatigued state, despite accumulated fatigue being an important risk factor for both hamstring strain (HS) and anterior cruciate ligament (ACL) injuries in professional soccer players. After the effect of different H:Q calculation methods were compared and contrasted, the influence of neuromuscular fatigue on the H:Q strength ratio and the association between fatigued and non-fatigued ratio scores were examined. Thirty-five professional soccer players performed a 30-repetition isokinetic fatigue test protocol. Peak knee joint moments were computed for each repetition, and the H:Q conventional ratio (H:QCR ) was calculated using several different, previously published, methods. Knee extensor and flexor moments were statistically decreased by the sixth repetition and continued to decrease until the end of the protocol. However, the H:Q ratio was statistically decreased at the end of the test due to a significant reduction in knee flexor moment (correlation between change in knee flexor moment and change in H:Q, r≈.80; P<.01). Moreover, H:Q measured in fatigue (ie, H:QFatigue ) at the end of the test was greater than H:QCR (1.25-1.38 vs 0.70, P<.01), these variables were weakly correlated (r=.39, P=.02), and subject rankings within the cohort based on H:QCR and H:QFatigue were different (rs =0.25, P=.15). The present data suggest that H:Q ratio measurement during a fatiguing test (H:QFatigue ) provides different outcomes to the traditional H:QCR . The observed significant hamstring fatigue and the difference, and weak correlation, between H:QCR and H:QFatigue indicate that useful information might be obtained with respect to the prediction of HS and ACL injury risk. The potential predictive value of H:QFatigue warrants validation in future prospective trials.

Cyclic fatigue resistance of R-Pilot, WaveOne Gold Glider, and ProGlider glide path instruments.

OBJECTIVE: The aim of the present study was to compare the cyclic fatigue resistance of R-Pilot (VDW; Munich, Germany) with ProGlider (Denstply Sirona; Ballaigues, Switzerland) and WaveOne Gold Glider (Denstply Sirona; Ballaigues, Switzerland) glide path instruments. MATERIALS AND METHODS: R-Pilot, ProGlider, and WaveOne Gold Glider instruments were collected (n = 15) and tested in a dynamic cyclic fatigue test device, which has an artificial canal with 60° angle of curvature and a 5-mm radius of curvature. All instruments were operated until fracture occurred, and both time to fracture (TF) and the lengths of the fractured fragments were recorded. Mean and standard deviations of TF and fragment length were calculated for each reciprocating system. TF data and fractured fragment length data were subjected to one-way ANOVA and post-hoc Tukey tests (P < 0.05). Also a Weibull analysis was performed on TF data. RESULTS: The cyclic fatigue resistance values of the WaveOne Gold Glider and R-Pilot were significantly higher than those of the ProGlider (P < 0.05), with no significant difference between them (P > 0.05). Weibull analysis revealed that WaveOne Gold Glider showed the highest predicted TF value for 99% survival rate, which was followed by R-Pilot and ProGlider. Regarding the length of the fractured tips, there were no significant differences among the instruments (P > 0.05). CONCLUSIONS: The reciprocating WaveOne Gold Glider and R-Pilot instruments had significantly higher cyclic fatigue resistance than rotary ProGlider instruments. CLINICAL RELEVANCE: This study reported that novel reciprocating glide path instruments exhibited higher cyclic fatigue resistance than rotating glide path instrument.

Motion Synchronous Composite Decoupling with Fewer Sensors on Multichannel Hydraulic Force Control for Aircraft Structural Loading Test System.

The aircraft full-scale fatigue test is widely used in the modern aircraft industry for the safety of flight. Generally, the aircraft full-scale fatigue test is achieved by structural loading; multiple hydraulic actuators are used to apply load for force control. The fatigue loading test takes approximately several years. A key challenge is how to accelerate the loading frequency to shorten the total test time. Nevertheless, when pluralities of hydraulic actuator simultaneously increase the loading frequency, the mutual coupling force from the low rigidity of the aircraft structure will cause a large loading error, meaning that the test cannot be implemented. Although it is possible to reduce error by adding sensors, the force sensors need to connect several kilometers of cable. This paper proposed a novel motion synchronous composite decoupling control strategy with fewer sensors. The control method compensates the negative coupling effect of the channels by integrating the command signals and feedback signals of all channels. It can suppress coupling force and reduce errors at higher frequencies, thereby shortening the experiment time. Opposed to traditional decoupling control methods, advantages of this strategy are that it only needs force sensors and it does not need additional displacement or velocity and acceleration sensors to collect state variables for building the state space. Furthermore, it has been experimentally verified that the new motion synchronous composite decoupling control method can indeed guarantee sufficient control accuracy when the test frequency is increased. The method has great economic significance for shortening test duration.

Effect of Cyclic Fatigue Tests on Aging and Their Translational Implications for Survival of All-Ceramic Tooth-Borne Single Crowns and Fixed Dental Prostheses.

PURPOSE: The objective of this systematic review was to elaborate the aging effect of cyclic fatigue tests on mechanical durability of all-ceramic single crowns and fixed dental prostheses (FDP). MATERIALS AND METHODS: Original scientific papers published in the MEDLINE (PubMed) database in English between 01/01/1950 and 12/31/2013 on cyclic loading on all-ceramics were included in this systematic review. The following MeSH terms, search terms, and their combinations were used: "in vitro," "stress mechanical," "crowns," "denture, partial, fixed," "dentistry," "fatigue," "all-ceramic," "zirconia," "fixed dental prosthesis," "FDP," "bridges," and "cyclic loading." Two reviewers performed screening and analyzed the data. Only the studies that reported on both static fracture strength and static fracture after fatigue of all-ceramic single crowns and FDPs that allowed comparison of aging effect through cyclic loading were included. RESULTS: The selection process resulted in a final sample of 14 journal articles. In total, 9 articles were identified related to all-ceramic single crowns, 3 of which were on anterior and 6 on posterior crowns, and 5 articles on 3-unit FDPs, all of which were on posterior FDPs. Fatigue cycles varied between minimum of 1000 to maximum 1,200,000 cycles for crowns and 10,000 to 2,000,000 cycles for 3-unit FDPs. The applied force during cyclic loading varied between 20 to 300 N for single crowns and 49 to 200 N for 3-unit FDPs. For the 3-unit FDPs, fracture strength results showed slightly decreased values after cyclic loading (659 ± 182 to 2333 ± 183 N) compared to static loading only (841 ± 244 to 2434 ± 154 N). For crowns similar trends were not observed, but cyclic loading decreased the fracture strength in only some materials after cyclic loading (659 ± 182 to 2333 ± 183 N) compared to static loading only (395 ± 96 to 2726 N). CONCLUSIONS: An inclination for decreased static fracture strength could be observed after cyclic loading of all-ceramic single crowns and FDPs, but this was material specific. Due to the heterogeneity of data such as aging, loading conditions, and fewer experimental groups, statistical analysis could not be performed. Cyclic loading tests require more standardized guidelines for testing and reporting.

Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue.

Fatigue affects most cancer patients and has numerous potential causes, including cancer itself and cancer treatment. Cancer-related fatigue (CRF) is not relieved by rest, can decrease quality of life, and has no FDA-approved therapy. Thyrotropin-releasing hormone (TRH) has been proposed as a potential novel treatment for CRF, but its efficacy against CRF remains largely untested. Thus, we tested the TRH analog, taltirelin (TAL), in mouse models of CRF. To model fatigue, we used a mouse model of chemotherapy, a mouse model of radiation therapy, and mice bearing colon 26 carcinoma tumors. We used the treadmill fatigue test to assess fatigue-like behavior after treatment with TAL. Additionally, we used wild-type and TRH receptor knockout mice to determine which TRH receptor was necessary for the actions of TAL. Tumor-bearing mice displayed muscle wasting and all models caused fatigue-like behavior, with mice running a shorter distance in the treadmill fatigue test than controls. TAL reversed fatigue-like behavior in all three models and the mouse TRH1 receptor was necessary for the effects of TAL. These data suggest that TAL may be useful in alleviating fatigue in all cancer patients and provide further support for evaluating TAL as a potential therapy for CRF in humans.