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1.
J Child Psychol Psychiatry ; 61(12): 1339-1348, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-32080848

RESUMEN

BACKGROUND: Self-conscious emotional reactivity and its physiological marker - blushing has been proposed to be an etiological mechanism of social anxiety disorder (SAD), but so far, untested in longitudinal designs. This study tested, for the first time, whether self-conscious emotional reactivity (indexed as physiological blushing) contributes to the development of SAD symptoms over and above social behavioral inhibition (BI), which has been identified as the strongest predictor of SAD development in early childhood. METHODS: One hundred fifteen children (45% boys) and their mothers and fathers participated at ages 2.5, 4.5, and 7.5 years. Social BI was observed at all time points in a stranger approach task, and physiological blushing (blood volume, blood pulse amplitude, and temperature increases) was measured during a public performance (singing) and watching back the performance at ages 4.5 and 7.5. Child early social anxiety was reported by both parents at 4.5 years, and SAD symptoms were diagnosed by clinicians and reported by both parents at 7.5 years. RESULTS: Higher social BI at 2.5 and 4.5 years predicted greater social anxiety at 4.5 years, which, in turn, predicted SAD symptoms at 7.5 years. Blushing (temperature increase) at 4.5 years predicted SAD symptoms at 7.5 years over and above the influence of social BI and early social anxiety. CONCLUSIONS: That blushing uniquely contributes to the development of SAD symptoms over and above social BI suggests two pathways to childhood SAD: one that entails early high social BI and an early onset of social anxiety symptoms, and the other that consists of heightened self-conscious emotional reactivity (i.e. blushing) in early childhood.


Asunto(s)
Sonrojo/psicología , Fobia Social/etiología , Fobia Social/psicología , Niño , Preescolar , Miedo , Femenino , Humanos , Estudios Longitudinales , Masculino , Padres/psicología
2.
Child Psychiatry Hum Dev ; 51(3): 461-470, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-32008126

RESUMEN

Maternal thyroid problems during pregnancy have been linked to neurocognitive impairments in children. While studies suggest that disorders of maternal thyroid function during pregnancy are associated with symptoms of mental health problems in children, little is known about the risk of clinically significant psychiatric disorders in adolescence. A sample of 2451 Canadian adolescents enrolled in the Ontario Child Health Study completed the Mini International Neuropsychiatric Interview for Children and Adolescents at 12-17 years of age. Their mothers self-reported thyroid problems during pregnancy. Gestational thyroid problems were associated with offspring oppositional defiant disorder (ODD; OR 3.73; 95% CI 1.69-8.24), conduct disorder (CD; OR 12.95; 95% CI 5.12-32.75), and social anxiety disorder (SAD; OR 6.25; 95% CI 2.53-15.47). Neither sex nor gestational age moderated associations between prenatal thyroid dysfunction and the majority of outcomes. School performance mediated 8% of the association between thyroid problems and SAD, 21% for CD and 53% for ODD.


Asunto(s)
Rendimiento Académico/estadística & datos numéricos , Déficit de la Atención y Trastornos de Conducta Disruptiva/epidemiología , Trastorno de la Conducta/epidemiología , Fobia Social/epidemiología , Efectos Tardíos de la Exposición Prenatal/epidemiología , Enfermedades de la Tiroides/epidemiología , Adolescente , Déficit de la Atención y Trastornos de Conducta Disruptiva/etiología , Niño , Trastorno de la Conducta/etiología , Femenino , Humanos , Masculino , Ontario/epidemiología , Fobia Social/etiología , Embarazo , Efectos Tardíos de la Exposición Prenatal/etiología , Enfermedades de la Tiroides/complicaciones
3.
Depress Anxiety ; 36(10): 960-967, 2019 10.
Artículo en Inglés | MEDLINE | ID: mdl-31437332

RESUMEN

BACKGROUND: Adolescence is characterized by an increased vulnerability for internalizing psychopathologies such as depression and anxiety. A positive association between anxiety and depression has consistently been found in research. However, the specific direction of this association is less clear. In this study, we investigated the temporal associations between (social) anxiety and depressive symptoms. Furthermore, the role of dependent interpersonal stress as a potential mediating factor in these temporal associations was examined. METHODS: Data were part of a larger longitudinal study on the emotional development of adolescents, which was initiated in February 2013. The total sample consisted of 2011 adolescents between the ages of 11 and 19. Data were analyzed using cross-lagged models. RESULTS: Bidirectional positive associations were found between social anxiety symptoms and depressive symptoms. However, dependent interpersonal stress was not a mediator in the link between social anxiety and depression. Our results indicate that dependent interpersonal stress seems to be particularly related to depressive symptoms and not to social anxiety symptoms. CONCLUSIONS: Findings suggest that bidirectional associations between social anxiety and depressive symptoms exist. This implies that clinicians should be specifically vigilant for the development of depressive symptoms in socially anxious adolescents and the development of social anxiety symptoms in depressed adolescents. Our findings further highlight the importance of targeting dependent interpersonal stress in the context of depression.


Asunto(s)
Depresión/psicología , Relaciones Interpersonales , Fobia Social/psicología , Estrés Psicológico/complicaciones , Adolescente , Niño , Depresión/complicaciones , Depresión/etiología , Emociones , Femenino , Humanos , Estudios Longitudinales , Masculino , Fobia Social/complicaciones , Fobia Social/etiología , Factores de Tiempo , Adulto Joven
4.
Int J Lang Commun Disord ; 54(6): 927-939, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-31364252

RESUMEN

BACKGROUND: iGlebe is a fully automated internet treatment program for adults who stutter that has been shown, in some cases, to reduce anxiety and effectively manage social anxiety disorder for many participants. No such automated internet treatment program exists for adolescents who stutter. AIMS: The present paper reports a Phase I trial of an adolescent version of the adult program: iBroadway. METHODS & PROCEDURES: Participants were 29 adolescents in the age range 12-17 years who were seeking cognitive-behaviour therapy (CBT) for anxiety associated with stuttering. The design was a non-randomized Phase I trial with outcome assessments at pre-treatment and immediately post-treatment after 5 months of access to the program. No contact by a clinical psychologist occurred during participant use of the program. Outcomes were a range of psychological, quality-of-life and stuttering severity measures. OUTCOMES & RESULTS: The compliance rate for the seven iBroadway modules over 5 months was extremely favourable for internet CBT, at 52.4%. There was evidence of treatment effects for (1) the number of DSM-IV mental health diagnoses with the Diagnostic Interview Schedule for Children; (2) the Unhelpful Thoughts and Beliefs About Stuttering scale; (3) the Subjective Units of Distress Scale; and (4) parent-reported speech satisfaction. CONCLUSIONS & IMPLICATIONS: Further development of iBroadway, the adolescent version of iGlebe, with Phase II trialling is warranted.


Asunto(s)
Terapia Cognitivo-Conductual/métodos , Internet , Fobia Social/terapia , Tartamudeo/terapia , Terapia Asistida por Computador/métodos , Adolescente , Niño , Femenino , Humanos , Masculino , Fobia Social/etiología , Escalas de Valoración Psiquiátrica , Autoinforme , Tartamudeo/psicología , Resultado del Tratamiento
5.
Neuro Endocrinol Lett ; 39(1): 9-18, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29604619

RESUMEN

OBJECTIVE: The purpose of the investigation was to explore the relationship between positive or negative symptoms, social anxiety, hope, personality, and self-stigma in patients with schizophrenia spectrum disorders. METHOD: 57 outpatients took part in this cross-sectional study. The structured interview M.I.N.I. International Neuropsychiatric Interview was used to confirm the diagnosis. All patients completed the Liebowitz Social Anxiety Scale, Internalized Stigma of Mental Illness Scale, Beck Depression Inventory-II, Beck Anxiety Inventory, Adult Dispositional Hope Scale, and Temperament and Character Inventory - Revised. The disorder severity was evaluated by Clinical Global Impression - Severity scale, and Positive and Negative Syndrome Scale. The patients were in a stabilized state that did not require hospitalization or modifications in the treatment. RESULTS: Both positive and negative symptoms of schizophrenia positively correlated with the length of the disorder, global severity of the disorder, the severity of the general and social anxiety symptoms, the severity of self-stigma, and negatively with personality traits Self-directedness and Cooperativeness. Only negative symptoms significantly positively correlated with the severity of depressive symptoms and personality trait Harm-avoidance and negatively with the hope and personality trait Persistence. Comorbidity with social phobia is associated with statistically significantly higher mean scores on the total score of schizophrenic symptomatology, negative subscale average rating, and general psychopathological items measured by PANSS. Patient with comorbid depression would experience a higher level of negative symptomatology than patients without such comorbidity.


Asunto(s)
Ansiedad/psicología , Depresión/psicología , Personalidad , Esquizofrenia/complicaciones , Psicología del Esquizofrénico , Autoimagen , Adolescente , Adulto , Anciano , Antipsicóticos/uso terapéutico , Ansiedad/etiología , Estudios Transversales , Depresión/etiología , Femenino , Humanos , Entrevista Psicológica , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Fobia Social/etiología , Fobia Social/psicología , Escalas de Valoración Psiquiátrica , Esquizofrenia/tratamiento farmacológico , Adulto Joven
6.
Psychol Med ; 46(9): 1875-83, 2016 07.
Artículo en Inglés | MEDLINE | ID: mdl-26979565

RESUMEN

BACKGROUND: Bullying victimization in childhood is associated with a broad array of serious mental health disturbances, including anxiety, depression, and suicidal ideation and behavior. The key goal of this study was to evaluate whether bullying victimization is a true environmental risk factor for psychiatric disturbance using data from 145 bully-discordant monozygotic (MZ) juvenile twin pairs from the Virginia Twin Study of Adolescent Behavioral Development (VTSABD) and their follow-up into young adulthood. METHOD: Since MZ twins share an identical genotype and familial environment, a higher rate of psychiatric disturbance in a bullied MZ twin compared to their non-bullied MZ co-twin would be evidence of an environmental impact of bullying victimization. Environmental correlations between being bullied and the different psychiatric traits were estimated by fitting structural equation models to the full sample of MZ and DZ twins (N = 2824). Environmental associations were further explored using the longitudinal data on the bullying-discordant MZ twins. RESULTS: Being bullied was associated with a wide range of psychiatric disorders in both children and young adults. The analysis of data on the MZ-discordant twins supports a genuine environmental impact of bullying victimization on childhood social anxiety [odds ratio (OR) 1.7], separation anxiety (OR 1.9), and young adult suicidal ideation (OR 1.3). There was a shared genetic influence on social anxiety and bullying victimization, consistent with social anxiety being both an antecedent and consequence of being bullied. CONCLUSION: Bullying victimization in childhood is a significant environmental trauma and should be included in any mental health assessment of children and young adults.


Asunto(s)
Ansiedad de Separación/epidemiología , Acoso Escolar/estadística & datos numéricos , Víctimas de Crimen/estadística & datos numéricos , Fobia Social/epidemiología , Ideación Suicida , Adolescente , Adulto , Ansiedad de Separación/etiología , Niño , Enfermedades en Gemelos/epidemiología , Femenino , Humanos , Estudios Longitudinales , Masculino , Fobia Social/etiología , Gemelos Monocigóticos , Adulto Joven
7.
Br J Dermatol ; 175(5): 930-936, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27169607

RESUMEN

BACKGROUND: Mindfulness, defined as purposively and nonjudgementally paying attention in the present moment, could be used within psychosocial interventions to reduce the distress associated with social anxiety and avoidance found in many skin conditions. However, little is known about the relationship between naturally occurring levels of mindfulness and distress in dermatology patients. OBJECTIVES: To examine the relationship between mindfulness and psychosocial distress in a dermatological population. It was hypothesized that higher levels of mindfulness would be associated with lower levels of social anxiety, anxiety, depression and skin shame, and with better quality of life. METHODS: Adult dermatology outpatients (n = 120) from one hospital completed items assessing subjective severity, skin shame, fear of negative evaluation, anxiety and depression, quality of life, and levels of mindfulness. RESULTS: Considering depression, 14% reported mild, 5% moderate and 2·5% severe symptoms. For anxiety, 22% reported mild, 23% moderate and 6% severe symptoms. In addition, 33·4% reported clinically significant social anxiety. After controlling for subjective severity, mindfulness explained an additional 19% of the variance in depression, 39% in anxiety, 41% in social anxiety, 13% in skin shame and 6% in dermatological quality of life. One specific facet of mindfulness (acting with awareness) was found to be the most consistent predictor of distress. CONCLUSIONS: The findings indicate that higher levels of mindfulness are associated with lower distress. This suggests that facilitating mindfulness may be helpful in reducing distress in dermatology patients, and the use of mindfulness techniques warrants further investigation.


Asunto(s)
Atención Plena , Calidad de Vida , Enfermedades de la Piel/psicología , Estrés Psicológico/etiología , Trastorno Depresivo/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fobia Social/etiología , Vergüenza
9.
Schizophr Bull ; 47(5): 1218-1242, 2021 08 21.
Artículo en Inglés | MEDLINE | ID: mdl-33778868

RESUMEN

Social anxiety is common in psychosis and associated with impaired functioning, poorer quality of life, and higher symptom severity. This study systematically reviewed factors maintaining social anxiety in people with attenuated, transient, or persistent psychotic experiences. Other correlates of social anxiety were also examined. MEDLINE, Embase, CENTRAL, and PsycINFO were searched for relevant literature up to October 19, 2020. Forty-eight articles were eligible for narrative synthesis: 38 cross-sectional studies, 8 prospective studies, 1 uncontrolled trial, and 1 qualitative study. From 12060 participants, the majority was general population (n = 8771), followed by psychosis samples (n = 2532) and those at high risk of psychosis (n = 757). The methodological quality and risk of bias were assessed using the Mixed Methods Appraisal Tool. Ninety percent of studies were rated as high to very-high quality. Poorer quality studies typically failed to adequately control for confounds and provided insufficient information on the measurement validity and reliability. Prominent psychological factors maintaining social anxiety included self-perceptions of stigma and shame. Common correlates of social anxiety included poorer functioning and lower quality of life. In conclusion, stigma and shame could be targeted as a causal mechanism in future interventional studies. The integration of findings from this review lead us to propose a new theoretical model to guide future intervention research.


Asunto(s)
Fobia Social/fisiopatología , Trastornos Psicóticos/fisiopatología , Esquizofrenia/fisiopatología , Psicología del Esquizofrénico , Autoimagen , Vergüenza , Estigma Social , Humanos , Fobia Social/etiología , Trastornos Psicóticos/complicaciones , Esquizofrenia/complicaciones
10.
Sci Rep ; 11(1): 18392, 2021 09 15.
Artículo en Inglés | MEDLINE | ID: mdl-34526518

RESUMEN

Mechanisms underlying anxiety disorders remain elusive despite the discovery of several associated genes. We constructed the protein-protein interaction networks (interactomes) of six anxiety disorders and noted enrichment for striatal expression among common genes in the interactomes. Five of these interactomes shared distinctive overlaps with the interactomes of genes that were differentially expressed in two striatal compartments (striosomes and matrix). Generalized anxiety disorder and social anxiety disorder interactomes showed exclusive and statistically significant overlaps with the striosome and matrix interactomes, respectively. Systematic gene expression analysis with the anxiety disorder interactomes constrained to contain only those genes that were shared with striatal compartment interactomes revealed a bifurcation among the disorders, which was influenced by the anterior cingulate cortex, nucleus accumbens, amygdala and hippocampus, and the dopaminergic signaling pathway. Our results indicate that the functionally distinct striatal pathways constituted by the striosome and the matrix may influence the etiological differentiation of various anxiety disorders.


Asunto(s)
Ansiedad/etiología , Ansiedad/metabolismo , Biomarcadores , Conectoma , Cuerpo Estriado/metabolismo , Fobia Social/etiología , Fobia Social/metabolismo , Citidina Desaminasa/genética , Citidina Desaminasa/metabolismo , Susceptibilidad a Enfermedades , Perfilación de la Expresión Génica , Regulación de la Expresión Génica , Redes Reguladoras de Genes , Humanos , Vías Nerviosas , Mapeo de Interacción de Proteínas , Mapas de Interacción de Proteínas , Transducción de Señal
11.
Rev Neurol ; 70(2): 45-52, 2020 Jan 16.
Artículo en Español, Inglés | MEDLINE | ID: mdl-31930470

RESUMEN

INTRODUCTION: Several studies have found that individuals with multiple sclerosis (MS) experience relatively high rates of anxiety and depression; however, there are few reports about social anxiety in individuals with MS. AIM: To analyze the prevalence of social anxiety disorder and other psychiatric comorbidities in MS patients compared to matched controls. SUBJECTS AND METHODS: We included 50 patients with MS that were seen during regularly scheduled visits and 50 sex- and age-matched participants from the general population within a six-month interval. All included participants completed the Social Phobia Inventory (SPIN) and the Depression, Anxiety and Stress Scale with 21 items (DASS-21). We defined clinically significant social anxiety symptoms as SPIN scores = 19. RESULTS: The MS patients' mean age was 41.9 years (54% female). The self-reported psychosocial assessments showed that MS participants were more likely to present positive social anxiety symptoms (OR = 7.37; 95% CI = 1.99-27.30; p < 0.001), depression (OR = 3.76; 95% CI = 1.41-10.10; p = 0.006), stress (OR = 2.67; 95% CI = 1.09-6.52; p = 0.029), and general anxiety (OR = 4.70; 95% CI = 1.93-11.40; p < 0.001) than the general population. There were moderate correlations between social anxiety and depression (p = 0,006), general anxiety (p = 0,001), and stress (p < 0,001) in MS patients. CONCLUSIONS: Patients with MS had a higher risk of presenting social anxiety symptoms than a matched control group in a Hispanic population.


TITLE: Trastorno de ansiedad social en pacientes con esclerosis múltiple: estudio poblacional de casos y controles en Ecuador.Introducción. Varios estudios han encontrado que individuos con esclerosis múltiple (EM) presentan tasas altas de ansiedad y depresión; sin embargo, hay pocos informes sobre ansiedad social en individuos con EM. Objetivo. Analizar la prevalencia del trastorno de ansiedad social y otras comorbilidades psiquiátricas en pacientes con EM en comparación con los controles pareados. Sujetos y métodos. Durante un intervalo de seis meses, incluimos a 50 pacientes con EM que fueron observados durante visitas programadas regularmente y a 50 participantes de la población general pareados por sexo y edad. Todos los participantes completaron el inventario de fobia social (SPIN) y la escala de depresión, ansiedad y estrés de 21 ítems. Definimos síntomas de ansiedad social clínicamente significativos los que tenían un resultado en el SPIN mayor o igual a 19. Resultados. La edad media de los pacientes con EM era de 41,9 años (el 54%, mujeres). Las evaluaciones psicológicas notificadas demostraron que los participantes con EM tenían más probabilidad de presentar síntomas positivos de ansiedad social (OR = 7,37; IC 95% = 1,99-27,30; p < 0,001), depresión (OR = 3,76; IC 95% = 1,41-10,10; p = 0,006), estrés (OR = 2,67; IC 95% = 1,09-6,52; p = 0,029) y ansiedad general (OR = 4,70; IC 95% = 1,93-11,40; p < 0,001) que la población general. Se observaron correlaciones moderadas entre ansiedad social y depresión (p = 0,006), ansiedad general (p = 0,001) y estrés (p < 0,001) en los pacientes con EM. Conclusiones. Los pacientes con EM tienen un riesgo más elevado de presentar síntomas de ansiedad social que la población hispana en general.


Asunto(s)
Esclerosis Múltiple/complicaciones , Esclerosis Múltiple/psicología , Fobia Social/epidemiología , Fobia Social/etiología , Adulto , Estudios de Casos y Controles , Ecuador/epidemiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Prevalencia
12.
J Int Assoc Provid AIDS Care ; 19: 2325958220918953, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32274969

RESUMEN

The purpose of this study was to investigate the effect of stress management training on stigma and social phobia among HIV-positive women. This quasi-experimental pre- and posttest study was performed on a single group of 55 HIV-positive females Hamadan city, Iran, in 2018. The samples were taken through a convenience sampling method and the data collection tool were Berger HIV Stigma and Connor Social Phobia Scale. The mean scores of the stigma were 119.98 ± 21.15 and 94.78 ± 16.34 and social phobia were 24 ± 17.4 and 11.2 ± 9.68 before and after the intervention, respectively. The results of the paired sample t test indicated a significant difference in the stigma and social phobia mean scores before and after the intervention in HIV-positive women (P < .05). The results of the study revealed that stigma and social phobia are big challenges for HIV-positive women since these people are always judged by others and are subjected to labeling and rejection.


Asunto(s)
Educación/normas , Infecciones por VIH/psicología , Fobia Social/psicología , Estigma Social , Estrés Psicológico/prevención & control , Adulto , Manejo de la Enfermedad , Femenino , Humanos , Irán , Persona de Mediana Edad , Fobia Social/etiología , Fobia Social/virología , Estrés Psicológico/virología , Encuestas y Cuestionarios
13.
J Fluency Disord ; 65: 105767, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32535211

RESUMEN

PURPOSE: Adults who stutter (AWS) often develop social anxiety disorder. This study was to provide comparative data on the Liebowitz Social Anxiety Scale-Japanese version (LSAS-J) from AWS and non-stuttering adult controls. METHODS: LSAS-J, a 24-item self-reported survey of social phobia and avoidance across various daily situations, was administered to 130 AWS (Mean Age = 41.5 years, SD = 15.8, 111 males) and 114 non-stuttering adults (Mean Age = 39.5, SD = 14.9, 53 males). The test-retest reliability and internal consistency of the LSAS-J were assessed. A between-subject multivariate analysis of variance (MANOVA) was also conducted to determine whether attitude toward social anxiety differed between AWS and AWNS, or by age (<40 and ≥ 40 years old), or sex (female and male). RESULTS: AWS reported higher scores on both fear subscales of the LSAS-J. Age had no significant influence on the social anxiety levels reported by either participant group. Sex differences were found in the fear subscales, with females scoring higher on both fear subscales, although these were only marginally significant (p = .06). LSAS-J showed good test-retest reliability and high Cronbach's alpha coefficient, indicating that it is an internally consistent measure of attitudes about social anxiety. CONCLUSION: Given the similarly high incidence of social anxiety in adults in Japan who stutter compared with those in other countries, social anxiety should be identified and assessed during clinical decision making and before decisions are made about stuttering treatment. LSAS-J is an easy tool to administer, and showed reliable results of social phobia and avoidance for AWS.


Asunto(s)
Ansiedad/complicaciones , Fobia Social/etiología , Tartamudeo/complicaciones , Tartamudeo/psicología , Adolescente , Adulto , Ansiedad/epidemiología , Estudios de Casos y Controles , Miedo , Femenino , Humanos , Japón , Masculino , Persona de Mediana Edad , Fobia Social/patología , Prevalencia , Autoinforme , Conducta Social , Tartamudeo/patología , Encuestas y Cuestionarios
14.
Violence Against Women ; 26(8): 825-837, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-31053045

RESUMEN

We measured maladaptive daydreaming (MD) and psychosocial indices among 194 participants, aged 18-56 years: 99 female survivors of childhood sexual abuse (CSA) and 95 control respondents with no reported history of sexual abuse. Our data show that survivors of CSA scored higher on MD compared to controls. Survivors of CSA with probable MD scored higher on psychological distress, social phobia, and social isolation compared to survivors of CSA without suspected MD, implying that MD might exacerbate the psychosocial problems linked with CSA. MD psychological screening of female survivors of CSA and the development of a treatment module for MD could improve the quality of clinical services provided to survivors.


Asunto(s)
Adaptación Psicológica , Adultos Sobrevivientes del Maltrato a los Niños/psicología , Abuso Sexual Infantil/psicología , Fantasía , Fobia Social/etiología , Trauma Psicológico/etiología , Estrés Psicológico/etiología , Adolescente , Adulto , Estudios de Casos y Controles , Niño , Víctimas de Crimen/psicología , Femenino , Humanos , Incesto , Israel , Persona de Mediana Edad , Funcionamiento Psicosocial , Aislamiento Social , Sobrevivientes , Adulto Joven
15.
Int J Psychophysiol ; 136: 73-80, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-29859994

RESUMEN

Early life maltreatment (ELM) is the major single risk factor for impairments in social functioning and mental health in adulthood. One of the most prevalent and most rapidly increasing forms of ELM is emotional neglect. According to bio-behavioral synchrony assumptions, the oxytocin and attachment systems play an important mediating role in the interplay between emotional neglect and social dysfunctioning. Therefore, the aim of the present study was to investigate whether fear and avoidance of social functioning, two important and highly prevalent facets of social dysfunctioning in adulthood, are shaped by emotional neglect, plasma oxytocin levels and attachment representations. We assessed emotional neglect as well as other forms of ELM with the Childhood Trauma Questionnaire, current attachment representations with the Adult Attachment Projective Picture System, and fear and avoidance of social situations with the Liebowitz Social Anxiety Scale in a population-based sample of N = 121 men and women. Furthermore, 4.9 ml blood samples were drawn from each participant to assess peripheral plasma oxytocin levels. Applying a sequential mediation model, results revealed that emotional neglect was associated with lower plasma oxytocin levels which in turn were associated with insecure attachment representations which were related to elevated fear and avoidance of social situations (a1d21b2: F3,117 = 20.84, P < .001). Plasma oxytocin and current attachment representations hence fully and sequentially mediate the effects of emotional neglect on social fear and avoidance, two important facets of adult social dysfunctioning, confirming bio-behavioral synchrony assumptions.


Asunto(s)
Adultos Sobrevivientes del Maltrato a los Niños , Experiencias Adversas de la Infancia , Apego a Objetos , Oxitocina/sangre , Fobia Social , Conducta Social , Adolescente , Adulto , Femenino , Humanos , Masculino , Fobia Social/sangre , Fobia Social/etiología , Fobia Social/fisiopatología , Adulto Joven
16.
Atten Defic Hyperact Disord ; 11(4): 343-351, 2019 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30604169

RESUMEN

The association between social anxiety disorder (SAD) and attention-deficit/hyperactivity disorder (ADHD) is poorly established. In fact, increasing and converging evidences suggest that there is a close relationship between the two disorders. High comorbidity rate between these two disorders, follow-up studies showing high rates of later development of SAD in ADHD and treatment studies in which ADHD medications have been helpful for both conditions all indicate this relationship. Recently, we have published a hypothesis regarding the development of SAD secondary to ADHD. In this hypothesis, we recognized that patients with SAD seem to go through a prodromal period that we labeled as "pre-social anxiety." Detecting patients in this period before meeting full-blown SAD criteria provides early intervention and prevention of SAD. New, comprehensive follow-up studies which will investigate whether ADHD causes later SAD secondarily are needed. In the current review, taken into account our developmental hypothesis, we will discuss whether high comorbidity of SAD and ADHD is a chance finding (i.e., the two disorders are found in cases with no causal relationship between them) or can SAD develop secondarily due to childhood ADHD. Is there a prodrom period in patients with SAD as in cancer or psychosis patients? We are going to summarize the overlapping features of SAD and ADHD in terms of child/parents interaction and family issues, aversive childhood experiences, social skill deficits, and development of cognitive distortions.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad/complicaciones , Fobia Social/etiología , Síntomas Prodrómicos , Trastorno por Déficit de Atención con Hiperactividad/psicología , Humanos , Fobia Social/psicología
17.
J Abnorm Child Psychol ; 47(7): 1107-1120, 2019 07.
Artículo en Inglés | MEDLINE | ID: mdl-29696435

RESUMEN

Guided by a developmental psychopathology framework, research has increasingly focused on the interplay of genetics and environment as a predictor of different forms of psychopathology, including social anxiety. In these efforts, the polygenic nature of complex phenotypes such as social anxiety is increasingly recognized, but studies applying polygenic approaches are still scarce. In this study, we applied Principal Covariates Regression as a novel approach to creating polygenic components for the oxytocin system, which has recently been put forward as particularly relevant to social anxiety. Participants were 978 adolescents (49.4% girls; Mage T1 = 13.8 years). Across 3 years, questionnaires were used to assess adolescent social anxiety symptoms and multi-informant reports of parental psychological control and autonomy support. All adolescents were genotyped for 223 oxytocin single nucleotide polymorphisms (SNPs) in 14 genes. Using Principal Covariates Regression, these SNPs could be reduced to five polygenic components. Four components reflected the underlying linkage disequilibrium and ancestry structure, whereas the fifth component, which consisted of small contributions of many SNPs across multiple genes, was strongly positively associated with adolescent social anxiety symptoms, pointing to an index of genetic risk. Moreover, significant interactions were found with this polygenic component and the environmental variables of interest. Specifically, adolescents who scored high on this polygenic component and experienced less adequate parenting (i.e., high psychological control or low autonomy support) showed the highest levels of social anxiety. Implications of these findings are discussed in the context of individual-by-environment models.


Asunto(s)
Ansiedad/etiología , Ansiedad/genética , Interacción Gen-Ambiente , Oxitocina/genética , Relaciones Padres-Hijo , Responsabilidad Parental , Fobia Social/etiología , Fobia Social/genética , Adolescente , Femenino , Humanos , Estudios Longitudinales , Masculino , Herencia Multifactorial , Autonomía Personal , Polimorfismo de Nucleótido Simple
18.
J Psychol ; 153(6): 599-614, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30912711

RESUMEN

Previous attempts to identify personality traits that enhance inclination to social anxiety (SA) have been limited by a tendency to focus on selected traits in isolation, rather than examining their interactions. Additional research is needed to better understand whether and how these dimensions are linked to SA. In a prospective study, it was examined how interactions between the Big Five personality factors predict SA symptoms. A total of 135 individuals, aged 18-50 years, were recruited. Personality traits were measured at baseline, and SA symptoms were assessed one month later. Results showed that low emotional stability was an independent predictor of higher levels of SA. Additionally, two significant interactions emerged: the interactions between extraversion and openness, and between openness and agreeableness predicted SA symptoms. At high openness, higher extraversion was associated with significantly lower levels of SA, suggesting that the interaction provides incrementally greater protection against SA. Thus, extraverts are likely to be protected against social anxiety symptoms, but more so the more open they are. Moreover, at high levels of agreeableness, low openness has been shown to be uniquely predictive for higher levels of SA symptoms, indicating that the combined effect of openness with agreeableness may be more important to SA than either trait in isolation. These findings highlight the importance of testing interaction effects of personality traits on psychopathology.


Asunto(s)
Ansiedad/psicología , Emociones , Personalidad , Fobia Social/psicología , Adolescente , Adulto , Ansiedad/etiología , Ansiedad/prevención & control , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fobia Social/etiología , Fobia Social/prevención & control , Estudios Prospectivos , Psicopatología , Factores de Riesgo , Adulto Joven
19.
Int. j. clin. health psychol. (Internet) ; 23(2): 1-9, abr.-jun. 2023. ilus, tab
Artículo en Inglés | IBECS (España) | ID: ibc-213880

RESUMEN

Background: Social anxiety disorder (SAD) is a common mental health problem, and its core cognitive manifestation is the persistent fear of being evaluated, including both negatively (FNE) and positively (FPE). This study aimed to examine the longitudinal relationships of FNE, FPE and SAD and explore their neural basis. Methods: Three samples were retrieved in this study. First, the data of 649 college students who completed a survey and fMRI scan were used to explore the neural basis of FNE, FPE, and SAD symptoms. Next, the data of 450 participants who completed the same survey twice were used to examine the longitudinal relationships of the variables. Finally, the overlapping of the two samples (N = 288) who completed two surveys and the fMRI scan were used to establish a brain-behavior model. Results: Both FNE and FPE predicted SAD, and SAD also predicted FPE. The neural signals of subregions in prefrontal cortex were correlated with the scores of FNE, FPE and SAD. Abnormal prefrontal signals influenced SAD symptoms via fears of evaluation. Conclusions: Our findings explain the behavioral and neural underpinnings of social anxiety from a fear of evaluation angle. This contributes to a better theorical understanding of SAD and clinical practice. (AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto Joven , Miedo , Fobia Social/clasificación , Fobia Social/etiología , Encuestas y Cuestionarios , Espectroscopía de Resonancia Magnética , Universidades
20.
J Fluency Disord ; 56: 55-68, 2018 06.
Artículo en Inglés | MEDLINE | ID: mdl-29602052

RESUMEN

PURPOSE: Social anxiety disorder is a debilitating anxiety disorder associated with significant life impairment. The purpose of the present study is to evaluate overall functioning for adults who stutter with and without a diagnosis of social anxiety disorder. METHOD: Participants were 275 adults who stuttered (18-80 years), including 219 males (79.6%) and 56 females (20.4%), who were enrolled to commence speech treatment for stuttering. Comparisons were made between participants diagnosed with social anxiety disorder (n = 82, 29.8%) and those without that diagnosis (n = 193, 70.2%). RESULTS: Although the socially anxious group was significantly younger than the non-socially anxious group, no other demographic differences were found. When compared to the non-socially anxious group, the socially anxious group did not demonstrate significantly higher self-reported stuttering severity or percentage of syllables stuttered. Yet the socially anxious group reported more speech dissatisfaction and avoidance of speaking situations, significantly more psychological problems, and a greater negative impact of stuttering. CONCLUSION: Significant differences in speech and psychological variables between groups suggest that, despite not demonstrating more severe stuttering, socially anxious adults who stutter demonstrate more psychological difficulties and have a more negative view of their speech. The present findings suggest that the demographic status of adults who stutter is not worse for those with social anxiety disorder. These findings pertain to a clinical sample, and cannot be generalized to the wider population of adults who stutter from the general community. Further research is needed to understand the longer-term impact of social anxiety disorder for those who stutter.


Asunto(s)
Trastornos de Ansiedad/etiología , Fobia Social/etiología , Tartamudeo/complicaciones , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Trastornos de Ansiedad/patología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fobia Social/patología , Tartamudeo/patología , Adulto Joven
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