Riesgo de fenómenos tromboembólicos en pacientes con enfermedad inflamatoria intestinal / Risk of thromboembolic phernoma in patients with inflammatory bowel disease

RESUMEN

La enfermedad inflamatoria intestinal (EII) es un factor de riesgo independiente para presentar fenómenos tromboembólicos (FTE). Evaluamos la prevalencia y los posibles factores de riesgo asociados a presentar FTE en pacientes con EII en nuestro centro. Material y métodos Se recogieron los datos de forma retrospectiva desde enero de 1995 hasta diciembre de 2011, obteniendo un total de 23 pacientes. Un 61% había sido diagnosticado de enfermedad de Crohn (EC) y un 39% de colitis ulcerosa (CU) según los criterios habituales. Resultados Utilizando la clasificación de Montreal, el 58% de los pacientes con EC tenía un patrón inflamatorio (B1), el 25% un patrón estenosante (B2) y el 17% un patrón fistulizante (B3). Respecto a la localización, la mitad de los pacientes tenían afectación ileocólica (L3), un tercio afectación cólica (L2) y el resto afectación ileal (L1). Entre los pacientes con CU según la clasificación de Montreal, el 78% sufría una colitis extensa (E3), el 11% tenía afectación de colon izquierdo (E2) y el 11% (..) (AU)

ABSTRACT

Inflammatory bowel disease (IBD) is an independent risk factor for thromboembolic phenomena (TEP). We evaluated the prevalence and the possible risk factors associated with developing TEP in patients with IBD in our center. Material and methods: Data were retrospectively collected from January 1995 to December2011 from 23 patients. A total of 61% were diagnosed with Crohn’s disease (CD) and 39% with ulcerative colitis (UC) according to routine criteria. Results: When the Montreal classification was used, 58% of the patients with CD had an inflammatory pattern (B1), 25% a stenosing pattern (B2) and 17% a fistulizing pattern (B3). Half the patients had ileocolic involvement (L3), one-third had colonic involvement (L2) and the remainder had ileal involvement (L1). Among patients with UC according to the Montreal classification,78% had extensive colitis (E3), 11% had left colonic involvement (E2) and 11% had proctocolitis (E1). During the event, almost half the patients with UC had severe inflammatory activity (S3;44%), 33% had mild-moderate activity (S1 22%, S2 11%) and only 22% were in remission (S0).Overall, at the time of the TEP, 48% of the patients had mild-moderate activity and 22% had severe activity. Likewise, 44% were hospitalized at the time of the event. In UC, an increase in the prevalence of TEP was found in admitted patients (66%). None of the patients had a family history of TEP, two patients (9%) had associated thrombophilia and 26% were active smokers (..) (AU)