Dental cementum reviewed: development, structure, composition, regeneration and potential functions

ABSTRACT

This article reviews developmental and structural characteristics of cementum, a unique avascular mineralized tissue covering the root surface that forms the interface between root dentin and periodontalligament. Besides describing the types of cementum andcementogenesis, attention is given to recent advances in scientific understanding of the molecular and cellular aspects of the formation and regeneration of cementum. The understanding of the mechanisms involved in the dynamic of this tissue should allow for thedevelopment of new treatment strategies concerning the approach of the root surface affected by periodontal disease and periodontal regeneration techniques