The effect of carbon dioxide therapy on composite graft survival
Acta cir. bras
; 28(8): 589-593, Aug. 2013. ilus, graf
Article
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| LILACS
| ID: lil-680613
Biblioteca responsable:
BR1.1
ABSTRACT
PURPOSE:
To investigate the effect of carboxytherapy in auricular composite grafts in rabbits.METHODS:
An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen.RESULTS:
The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn't influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively).CONCLUSIONS:
Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.Palabras clave
Texto completo:
1
Banco de datos:
LILACS
Asunto principal:
Dióxido de Carbono
/
Pabellón Auricular
/
Supervivencia de Injerto
Límite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Asunto de la revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2013
Tipo del documento:
Article
País de afiliación:
Brasil