Aspiration flow optimized for nasal nitric oxide measurement.
Rhinology
; 37(2): 61-5, 1999 Jun.
Article
en En
| MEDLINE
| ID: mdl-10416250
ABSTRACT
The aim of the present study was to evaluate some of the factors which may influence the reliability of nasal NO measurements, and to optimize methods suitable for children and adults. Nasal nitric oxide (NO) output was determined by chemiluminescent analysis of aspirated samples in 16 adults and 6 children. With the velopharyngeal aperture closed, stable NO levels were obtained at flows ranging form 0.9 to 6.2 L/min. NO output averaged 401.0 +/- 145.4 nL/min./M2 in 6 children, 338.2 +/- 92.3 in 7 adult females and 268.6 +/- 70.2 in 9 adult males. Nasal NO output was independent of flow provided a stable plateau of NO value was reached. In this study, the optimal range of flows was 3.2-5.2 L/min. in adults and 2.2-3.2 L/min. in children. This enables selection of the most favorable flow to be chosen for individual subjects and situations.
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Banco de datos:
MEDLINE
Asunto principal:
Ventilación Pulmonar
/
Mucosa Nasal
/
Óxido Nítrico
Límite:
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Rhinology
Año:
1999
Tipo del documento:
Article