Platelet dysfunction in patients with vitamin B12 deficiency.
Acta Haematol
; 61(2): 75-9, 1979.
Article
en En
| MEDLINE
| ID: mdl-105547
10 cases of pernicious anaemia are reported in which 6 had abnormal aggregation with epinephrine, 3 with fibrinogen, 2 with ADP, and 2 with ristocetin. 5 patients had thrombocytopenia and 3 of these had a prolongation of the bleeding time. These abnormalities were normalized after vitamin B12 treatment. After treatment, platelet size changed toward a smaller diameter, but platelet size, however, was not significantly different from the normal platelet size distribution.
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Banco de datos:
MEDLINE
Asunto principal:
Trastornos de las Plaquetas Sanguíneas
/
Agregación Plaquetaria
/
Anemia Perniciosa
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Haematol
Año:
1979
Tipo del documento:
Article