Prevalence and predictors of skin disease in the Women's Interagency HIV Study (WIHS).
J Am Acad Dermatol
; 44(5): 785-8, 2001 May.
Article
en En
| MEDLINE
| ID: mdl-11312425
ABSTRACT
OBJECTIVE:
We attempted to determine the prevalence and predictors of skin disease in a cohort of women with and at risk for HIV infection.METHODS:
We analyzed baseline data from a multicenter longitudinal study of HIV infection in women.RESULTS:
A total of 2018 HIV-infected women and 557 HIV-uninfected women were included in this analysis. Skin abnormalities were reported more frequently among HIV-infected than uninfected women (63% vs 44%, respectively; odds ratio [OR] 2.10; 95% confidence interval [95% CI], 1.74-2.54). Infected women were also more likely to have more than 2 skin diagnoses (OR, 3.27; 95% CI, 1.31-8.16). Folliculitis, seborrheic dermatitis, herpes zoster, and onychomycosis were more common among HIV-infected women (P < .05). Independent predictors of abnormal findings on skin examination in the infected women were African American race (OR, 1.38; 95% CI, 1.07-1.77), injection drug use (OR, 2.74; 95% CI, 2.11-3.57), CD4(+) count less than 50 (OR, 1.68; 95% CI, 1.17-2.42), and high viral loads (100,000-499,999 = OR, 1.77; 95% CI, 1.32-2.37; > 499,999 = OR, 2.15; 95% CI, 1.42-3.27).CONCLUSION:
HIV infection was associated with a greater number of skin abnormalities and with specific dermatologic diagnoses. Skin abnormalities were also more common among women with CD4(+) cell depletion or higher viral load.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de la Piel
/
Infecciones por VIH
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos