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AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.
Petersen, Simone; Casellas, Rafael; Reina-San-Martin, Bernardo; Chen, Hua Tang; Difilippantonio, Michael J; Wilson, Patrick C; Hanitsch, Leif; Celeste, Arkady; Muramatsuk, Masamichi; Pilch, Duane R; Redon, Christophe; Ried, Thomas; Bonner, William M; Honjo, Tasuku; Nussenzweig, Michel C; Nussenzweig, André.
Afiliación
  • Petersen S; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Casellas R; Laboratory of Molecular Immunology, The Rockefeller University, and Howard Hughes Medical Institute, New York, New York 10021, USA.
  • Reina-San-Martin B; Laboratory of Molecular Immunology, The Rockefeller University, and Howard Hughes Medical Institute, New York, New York 10021, USA.
  • Chen HT; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Difilippantonio MJ; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Wilson PC; Laboratory of Molecular Immunology, The Rockefeller University, and Howard Hughes Medical Institute, New York, New York 10021, USA.
  • Hanitsch L; Laboratory of Molecular Immunology, The Rockefeller University, and Howard Hughes Medical Institute, New York, New York 10021, USA.
  • Celeste A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Muramatsuk M; Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
  • Pilch DR; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Redon C; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Ried T; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Bonner WM; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
  • Honjo T; Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
  • Nussenzweig MC; Laboratory of Molecular Immunology, The Rockefeller University, and Howard Hughes Medical Institute, New York, New York 10021, USA.
  • Nussenzweig A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Nature ; 414(6864): 660-665, 2001 Dec 06.
Article en En | MEDLINE | ID: mdl-11740565

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Histonas / Mutagénesis / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa Límite: Animals Idioma: En Revista: Nature Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Nucleares / Histonas / Mutagénesis / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa Límite: Animals Idioma: En Revista: Nature Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos