H2AX haploinsufficiency modifies genomic stability and tumor susceptibility.

Celeste, Arkady; Difilippantonio, Simone; Difilippantonio, Michael J; Fernandez-Capetillo, Oscar; Pilch, Duane R; Sedelnikova, Olga A; Eckhaus, Michael; Ried, Thomas; Bonner, William M; Nussenzweig, André

Celeste, Arkady; Difilippantonio, Simone; Difilippantonio, Michael J; Fernandez-Capetillo, Oscar; Pilch, Duane R; Sedelnikova, Olga A; Eckhaus, Michael; Ried, Thomas; Bonner, William M; Nussenzweig, André.

Afiliación

Celeste A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Difilippantonio S; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Difilippantonio MJ; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Fernandez-Capetillo O; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Pilch DR; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Sedelnikova OA; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Eckhaus M; Veterinary Resources Program, Office of Research Services, National Institutes of Health, Bethesda, Maryland 20892.
Ried T; Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Bonner WM; Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Nussenzweig A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

Cell ; 114(3): 371-383, 2003 Aug 08.

Article en En | MEDLINE | ID: mdl-12914701

Asunto(s)

Aberraciones Cromosómicas; ADN/metabolismo; Susceptibilidad a Enfermedades; Histonas/metabolismo; Animales; Linfocitos B/fisiología; Células Cultivadas; ADN/genética; ADN/efectos de la radiación; Daño del ADN; Reparación del ADN; Fibroblastos/citología; Fibroblastos/fisiología; Fibroblastos/efectos de la radiación; Rayos gamma; Histonas/genética; Cariotipificación; Linfoma/genética; Linfoma/metabolismo; Linfoma/patología; Ratones; Ratones Noqueados; Fosforilación; Tasa de Supervivencia; Linfocitos T/citología; Linfocitos T/fisiología; Proteína p53 Supresora de Tumor/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ADN / Histonas / Aberraciones Cromosómicas / Susceptibilidad a Enfermedades Límite: Animals Idioma: En Revista: Cell Año: 2003 Tipo del documento: Article

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