Depressive symptoms and age-related macular degeneration in older people: the cardiovascular health study.
Ophthalmic Epidemiol
; 14(3): 127-33, 2007.
Article
en En
| MEDLINE
| ID: mdl-17613847
ABSTRACT
PURPOSE:
To examine the association between age-related macular degeneration (AMD) and depressive symptoms.METHODS:
Population-based, cross-sectional study. A total of 2,194 persons aged 69-97 years were included in the current analyses. During the 1997-1998 examination, retinal photography from one randomly selected eye was graded for presence of early and late AMD using a modified Wisconsin AMD by Grading System. Depressive symptoms were assessed via a modified version of the Centers for Epidemiologic Studies Depression (CES-D) scale annually from 1989 through 1997-1998. Depressive symptoms were defined as a CES-D score of >9 (top quartile of CES-D score) at the 1997-1998 examination.RESULTS:
There were 338 (15.6%) individuals with early AMD and 29 (1.3%) with late AMD. Among them, 368 (16.8%) persons had depressive symptoms at the 1997-1998 examination. Depressive symptoms were not associated with early AMD (multivariable adjusted odds ratio [OR] 0.97; 95% confidence intervals [CI] 0.69-1.36) or late AMD (OR 1.15; 95% CI 0.38-3.46). Including persons using anti-depressive medications did not alter these associations (OR 0.98; 95% CI 0.74-1.32 for early AMD and OR 0.97; 95% CI 0.35-2.67 for late AMD). There was no association in multinomial logistic regression models of increasing quartiles of the CES-D scores with early or late AMD status.CONCLUSIONS:
Our study did not find an association between early AMD and depressive symptoms in older people.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Trastorno Depresivo
/
Degeneración Macular
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Ophthalmic Epidemiol
Asunto de la revista:
EPIDEMIOLOGIA
/
OFTALMOLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Australia