Shortening of cardiac action potential duration near an insulating boundary.
Math Med Biol
; 25(1): 21-36, 2008 Mar.
Article
en En
| MEDLINE
| ID: mdl-18343886
ABSTRACT
It is known, from both experiments and simulations, that cardiac action potentials are shortened near a non-conducting boundary. In the present paper, this effect is studied in a simple, two-current ionic model, with propagation restricted to a 1D fibre. An asymptotic approximation for the dependence of action potential duration on distance to the boundary is derived. This estimate agrees well with simulations.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Corazón
/
Modelos Cardiovasculares
Límite:
Animals
Idioma:
En
Revista:
Math Med Biol
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos