Early predictors of haemorrhage in acute febrile syndrome patients from Bucaramanga, Colombia: a dengue endemic area.
Singapore Med J
; 49(6): 480-2, 2008 Jun.
Article
en En
| MEDLINE
| ID: mdl-18581022
ABSTRACT
INTRODUCTION:
Spontaneous haemorrhage is an important cause of hospitalisation in dengue patients. Early predictors of these complications could help to make opportune decisions.METHODS:
We prospectively evaluated 51 febrile patients (without previous spontaneous haemorrhage), including 32 cases of dengue fever. Initial evaluation was performed during the first 96 hours after the onset of fever and included complete blood cell count and coagulation tests. Participants were followed-up daily until the seventh day of the disease.RESULTS:
Overall, 15 patients developed spontaneous haemorrhage during the follow-up. Tourniquet test and dengue infection were not associated with haemorrhage (p-value is greater than 0.2). In a logistic regression analysis, platelet count (odds-ratio [OR] 0.78; 95 percent confidence interval [CI] 0.65-0.94) and partial thromboplastin time (OR 1.78; 95 percent CI 1.06-2.99) were independently associated with spontaneous haemorrhage.CONCLUSION:
Early alterations in platelet count and coagulation test could predict spontaneous bleeding in the acute febrile syndrome.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Endémicas
/
Dengue Grave
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
País/Región como asunto:
America do sul
/
Colombia
Idioma:
En
Revista:
Singapore Med J
Año:
2008
Tipo del documento:
Article
País de afiliación:
Colombia