Preparation of highly photosensitizing liposomes with fullerene-doped lipid bilayer using dispersion-controllable molecular exchange reactions.
Org Lett
; 10(18): 4077-80, 2008 Sep 18.
Article
en En
| MEDLINE
| ID: mdl-18707108
ABSTRACT
Fullerene-containing liposomes with high photosensitization ability were prepared. Disaggregated fullerenes were efficiently injected into the bilayer of liposomes by a phototriggered molecular exchange reaction. These liposomes showed far higher photoreactivity than liposomes thermally produced by heating and microwave irradiation. This result indicates that control of self-aggregation of fullerene leads to a high quantum yield for the photoreaction because of the suppression of self-quenching of photoexcited fullerenes.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Fármacos Fotosensibilizantes
/
Fulerenos
/
Membrana Dobles de Lípidos
/
Liposomas
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Japón