Bombesin stimulates a high affinity GTPase activity in membranes of Swiss 3T3 fibroblasts.
Biochim Biophys Acta
; 1092(3): 397-400, 1991 May 17.
Article
en En
| MEDLINE
| ID: mdl-1904778
ABSTRACT
Peptides of the bombesin family are mitogenic for Swiss 3T3 fibroblasts and in these cells stimulate the turnover of polyphosphoinositides. Recent studies have suggested that G protein(s) may be involved in the signal transduction pathway triggered by bombesin. In this study we have found and characterized a high affinity GTPase activity stimulated by bombesin in membranes of Swiss 3T3 fibroblasts. Our results support the involvement of a G protein in the response of Swiss 3T3 cells to bombesin.
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Banco de datos:
MEDLINE
Asunto principal:
Bombesina
/
Membrana Celular
/
GTP Fosfohidrolasas
Límite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1991
Tipo del documento:
Article
País de afiliación:
Italia