T-regulatory cell modulation: the future of cancer immunotherapy?

Nizar, S; Copier, J; Meyer, B; Bodman-Smith, M; Galustian, C; Kumar, D; Dalgleish, A

Nizar, S; Copier, J; Meyer, B; Bodman-Smith, M; Galustian, C; Kumar, D; Dalgleish, A.

Afiliación

Nizar S; Department of Cellular and Molecular Medicine, St George's University of London, London, UK.

Br J Cancer ; 100(11): 1697-703, 2009 Jun 02.

Article en En | MEDLINE | ID: mdl-19384299

ABSTRACT

ABSTRACT

T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients.

Asunto(s)

Inmunoterapia; Neoplasias/inmunología; Neoplasias/terapia; Linfocitos T Reguladores/inmunología; Animales; Antineoplásicos/uso terapéutico; Ensayos Clínicos como Asunto; Humanos; Neoplasias/patología

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T Reguladores / Inmunoterapia / Neoplasias Límite: Animals / Humans Idioma: En Revista: Br J Cancer Año: 2009 Tipo del documento: Article País de afiliación: Reino Unido

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