No correlation between giant cell arteritis and Chlamydia pneumoniae infection: investigation of 189 patients by standard and improved PCR methods.

Njau, Florence; Ness, Thomas; Wittkop, Ulrike; Pancratz, Thorsten; Eickhoff, Meike; Hudson, Alan P; Haller, Hermann; Wagner, Annette D

Njau, Florence; Ness, Thomas; Wittkop, Ulrike; Pancratz, Thorsten; Eickhoff, Meike; Hudson, Alan P; Haller, Hermann; Wagner, Annette D.

Afiliación

Njau F; Department of Internal Medicine, Division of Nephrology, Hannover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany. fnjau@yahoo.com

J Clin Microbiol ; 47(6): 1899-901, 2009 Jun.

Article en En | MEDLINE | ID: mdl-19386842

ABSTRACT

ABSTRACT

A total of 189 temporal artery biopsy samples from giant cell arteritis (GCA) patients were investigated using sensitive PCR targeting Chlamydia pneumoniae. Chlamydial DNA was detected in 17 samples, 11 of which were positive for chlamydial antigens. Our data did not reveal strong evidence that C. pneumoniae plays an important role in the pathogenesis of GCA.

Asunto(s)

Infecciones por Chlamydophila/complicaciones; Chlamydophila pneumoniae/aislamiento & purificación; Arteritis de Células Gigantes/etiología; Anciano; Antígenos Bacterianos/aislamiento & purificación; Chlamydophila pneumoniae/genética; ADN Bacteriano/aislamiento & purificación; Femenino; Humanos; Inmunoensayo/métodos; Masculino; Reacción en Cadena de la Polimerasa/métodos

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arteritis de Células Gigantes / Chlamydophila pneumoniae / Infecciones por Chlamydophila Límite: Aged / Female / Humans / Male Idioma: En Revista: J Clin Microbiol Año: 2009 Tipo del documento: Article País de afiliación: Alemania

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