Synthesis of Oxadiazole-2-oxide Analogues as Potential Antischistosomal Agents.
Tetrahedron Lett
; 50(15): 1710-1713, 2009 Apr.
Article
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| MEDLINE
| ID: mdl-19802367
The synthesis of several 1,2,5-oxadiazole-2-oxide (Furoxan) analogues is described herein. These compounds were prepared in an effort to probe the SAR around the phenyl substituent and oxadiazole core for our studies toward thioredoxin-glutathione reductase (TGR) inhibition and anti-schistosomal activity.
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MEDLINE
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En
Revista:
Tetrahedron Lett
Año:
2009
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Article
País de afiliación:
Estados Unidos