The Janus-SAM approach for the flexible functionalization of gold and titanium oxide surfaces.
Small
; 6(3): 465-70, 2010 Feb 05.
Article
en En
| MEDLINE
| ID: mdl-19924741
ABSTRACT
A novel approach is developed to address the requirement of multiple stamps and inks for microcontact printing (microCP) onto different substrate surfaces. This approach relies on microCP one divalent molecule, which is able to form Janus self-assembled monolayers (JSAMs) with a labile cleavable centre, thus providing a facile method for the chemical derivatization of different substrate surfaces. This study presents an answer to the challenges presented within a highly versatile application, microCP. N-(3-diethylphosphatoxy)propyl-11-mercaptoundecanamide is used for the first time as an ink for microCP onto both gold and titanium oxide surfaces, utilizing the same polydimethylsiloxane stamp. Following printing, the JSAMs are enzymatically treated on these two different substrates to reveal different functional groups. The newly formed surfaces are subjected to additional surface reactions and used for the chemisorption of bovine serum albumin. At each stage, these JSAMs are characterized by X-ray photoelectron spectroscopy and dynamic water-contact-angle measurements. Confocal laser scanning microscopy is used for the characterization of the adsorbed proteins.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Titanio
/
Nanotecnología
/
Oro
Límite:
Animals
Idioma:
En
Revista:
Small
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Alemania