Hymenopsins A and B and a macrophorin analogue from a fungicolous Hymenopsis sp.
J Nat Prod
; 73(3): 404-8, 2010 Mar 26.
Article
en En
| MEDLINE
| ID: mdl-19928955
ABSTRACT
Hymenopsin A (1), hymenopsin B (2), and a new macrophorin analogue, 2',3'-epoxy-13-hydroxy-4'-oxomacrophorin A (3), have been isolated from a fungicolous isolate of Hymenopsis sp. (MYC-1703; NRRL 37638). The structures and relative configurations of these compounds were assigned on the basis of 2D NMR and MS data, and the identity of 1 was confirmed by X-ray crystallographic analysis. The absolute configuration of 2 was proposed on the basis of CD analysis using both empirical and computational methods. Compounds 2 and 3 showed antibacterial activity against Staphylococcus aureus and Bacillus subtilis. Compound 3 was also active against Aspergillus flavus and Fusarium verticillioides.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Hongos
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Nat Prod
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos