Insulator base pairs for lighting-up perylenediimide in a DNA duplex.
Chemistry
; 16(38): 11554-7, 2010 Oct 11.
Article
en En
| MEDLINE
| ID: mdl-20799301
ABSTRACT
Quenched Perylenediimide (PDI) is highly quenched by nucleobases, which greatly restricts its application as a fluorescent probe. Here, we propose "insulator base pairs" tethering cyclohexane ring through D-threoninol. When "insulator base pairs" were inserted between PDI and nucleobases, the quantum yield of PDI drastically increased several thousand-fold. The "insulator base pairs" reported here also have the potential to increase the quantum yields of other fluorophores.
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MEDLINE
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Perileno
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Idioma:
En
Revista:
Chemistry
Asunto de la revista:
QUIMICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Japón