Separation anxiety disorder in OCD.
Depress Anxiety
; 28(3): 256-62, 2011 Mar.
Article
en En
| MEDLINE
| ID: mdl-21308883
ABSTRACT
BACKGROUND:
A history of separation anxiety disorder (SAD) is frequently reported by patients with obsessive-compulsive disorder (OCD). The purpose of this study was to determine if there are clinical differences between OCD-affected individuals with, versus without, a history of SAD.METHODS:
Using data collected during the OCD Collaborative Genetic Study, we studied 470 adult OCD participants; 80 had a history of SAD, whereas 390 did not. These two groups were compared as to onset and severity of OCD, lifetime prevalence of Axis I disorders, and number of personality disorder traits.RESULTS:
OCD participants with a history of SAD were significantly younger than the non-SAD group (mean, 34.2 versus 42.2 years; P<.001). They had an earlier age of onset of OCD symptoms (mean, 8.0 versus 10.5 years; P<.003) and more severe OCD, as measured by the Yale-Brown Obsessive Compulsive Scale (mean, 27.5 versus 25.0; P<.005). In addition, those with a history of SAD had a significantly greater lifetime prevalence of agoraphobia (odds ratio (OR) = 2.52, 95% confidence interval (CI) = 1.4-4.6, P<.003), panic disorder (OR = 1.84, CI = 1.03-3.3 P<.04), social phobia (OR = 1.69, CI 1.01-2.8, P<.048), after adjusting for age at interview, age at onset of OCD, and OCD severity in logistic regression models. There was a strong relationship between the number of dependent personality disorder traits and SAD (adjusted OR = 1.42, CI = 1.2-1.6, P<.001).CONCLUSIONS:
A history of SAD is associated with anxiety disorders and dependent personality disorder traits in individuals with OCD.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ansiedad de Separación
/
Trastorno Obsesivo Compulsivo
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Depress Anxiety
Asunto de la revista:
PSIQUIATRIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos