New driver for lipid synthesis.
Cell
; 147(4): 719-21, 2011 Nov 11.
Article
en En
| MEDLINE
| ID: mdl-22078872
ABSTRACT
Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity. These findings suggest a link between lipid synthesis and cellular pathways involved in methylation.
Texto completo:
1
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Cell
Año:
2011
Tipo del documento:
Article
País de afiliación:
Países Bajos