Biological evaluation of RBx-0128, a potent and selective dipeptidyl peptidase-IV inhibitor in type 2 diabetes genetic model.

Davis, Joseph A; Kumar, Pucha S; Singh, Shuchita; Surender, A; Roy, Subhasis; Khanna, Vivek; Sethi, Sachin; Pal, Chanchan; Sharma, Lalima; Benjamin, Biju; Mittra, Shivani; Sattigeri, Jitendra; Bansal, Vinay S

Davis, Joseph A; Kumar, Pucha S; Singh, Shuchita; Surender, A; Roy, Subhasis; Khanna, Vivek; Sethi, Sachin; Pal, Chanchan; Sharma, Lalima; Benjamin, Biju; Mittra, Shivani; Sattigeri, Jitendra; Bansal, Vinay S.

Afiliación

Davis JA; Department of Pharmacology, New Drug Discovery Research, Ranbaxy Research Laboratories, Gurgaon, Haryana, India.

Indian J Pharmacol ; 44(6): 759-64, 2012.

Article en En | MEDLINE | ID: mdl-23248408

Asunto(s)

Diabetes Mellitus Tipo 2/tratamiento farmacológico; Inhibidores de la Dipeptidil-Peptidasa IV/uso terapéutico; Animales; Diabetes Mellitus Tipo 2/sangre; Dipeptidil Peptidasa 4/metabolismo; Inhibidores de la Dipeptidil-Peptidasa IV/sangre; Inhibidores de la Dipeptidil-Peptidasa IV/farmacología; Femenino; Péptido 1 Similar al Glucagón/sangre; Prueba de Tolerancia a la Glucosa; Humanos; Insulina/sangre; Masculino; Ratones; Ratones Obesos; Ratas; Ratas Wistar

Palabras clave

Antidiabetic effect; dipeptidyl peptidase-IV inhibitor; glucagon-like peptide-1; oral glucose tolerance test; sitagliptin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Inhibidores de la Dipeptidil-Peptidasa IV Límite: Animals / Female / Humans / Male Idioma: En Revista: Indian J Pharmacol Año: 2012 Tipo del documento: Article País de afiliación: India

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