Allergen-specific immunotherapy: update on immunological mechanisms.
Allergol Immunopathol (Madr)
; 41(4): 265-72, 2013.
Article
en En
| MEDLINE
| ID: mdl-23332741
ABSTRACT
UNLABELLED Immunotherapy selectively modulates the allergen-specific immune response. It involves the gradual administration of increasing amounts of allergen for the purpose of inducing protective immunological changes and it is the only curative approach for specific type I allergy. AIM:
Description of the allergic inflammation.- Comprehension of the early cellular changes after specific immunotherapy has been initiated. Exposure of the mechanisms involved in tolerance induction by regulatory T cells (Treg) with the inhibition of the Th2 responses. Comprehension of IL-10 and transforming growth factor (TGF- ) roles. Explanation of specific IgE, IgG and IgA changes. Description of the suppression of inflammatory responses during immunotherapy.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Alérgenos
/
Desensibilización Inmunológica
/
Hipersensibilidad Inmediata
Límite:
Humans
Idioma:
En
Revista:
Allergol Immunopathol (Madr)
Año:
2013
Tipo del documento:
Article
País de afiliación:
España