[Prevention of tuberculosis: current approaches to development of vaccines].
Vestn Ross Akad Med Nauk
; (11): 45-52, 2012.
Article
en Ru
| MEDLINE
| ID: mdl-23457981
ABSTRACT
This review is focused on recent advances in development of new vaccines for the prevention of tuberculosis. The main reasons for lack of BCG vaccine efficacy in different populations and geographic regions are presented. Design of new vaccines based on live modified strains of Mycobacterium bovis BCG, attenuated strains of Mycobacterium tuberculosis, recombinant proteins and viral vectors is considered in the specific examples. The usage of the heterologous "prime-boost" vaccination strategy against tuberculosis is discussed.
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Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis
/
Vacunación
/
Vacunas contra la Tuberculosis
Límite:
Animals
/
Humans
Idioma:
Ru
Revista:
Vestn Ross Akad Med Nauk
Asunto de la revista:
MEDICINA
Año:
2012
Tipo del documento:
Article