Diagnosis and treatment of unilateral forms of primary aldosteronism.
Curr Hypertens Rev
; 9(2): 156-65, 2013 May.
Article
en En
| MEDLINE
| ID: mdl-23971697
ABSTRACT
Primary aldosteronism (PA) is now recognized as the most frequent form of secondary arterial hypertension. The importance of a correct and prompt diagnosis of PA is determined by its relevant prevalence, its increased cardiovascular risk compared to essential hypertension and by the possibility of reversing this increased risk with a targeted therapy. Surgical treatment of unilateral forms of PA (mainly aldosterone-producing adenomas) is at present recommended in well-selected patients because of its cost-effectiveness. Therefore, subtype differentiation of PA forms is of fundamental importance, and available guidelines recommend contrast-enhanced CT-scanning and adrenal venous sampling (AVS) as the main diagnostic tests for this purpose. In this review, we discuss the value of adrenal non-invasive imaging and AVS, the recent advances in complementary tests and, finally, the available data on the outcome of surgical treatment for PA.
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Banco de datos:
MEDLINE
Asunto principal:
Adrenalectomía
/
Hiperaldosteronismo
/
Hipertensión
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Hypertens Rev
Año:
2013
Tipo del documento:
Article
País de afiliación:
Italia