Fitness and physical activity in youth with type 1 diabetes mellitus in good or poor glycemic control.
Pediatr Diabetes
; 16(1): 48-57, 2015 Feb.
Article
en En
| MEDLINE
| ID: mdl-24444038
ABSTRACT
BACKGROUND:
Patients with type 1 diabetes mellitus (T1DM) may experience poor muscle health as a result of chronic hyperglycemia. Despite this, muscle function in children with T1DM with good or poor glycemic control has yet to be examined in detail.OBJECTIVE:
To assess differences in muscle-related fitness variables in children with T1DM with good glycemic control (T1DM-G), as well as those with poor glycemic control (T1DM-P), and non-diabetic, healthy controls.SUBJECTS:
Eight children with T1DM-G [glycosylated hemoglobin (HbA1c) ≤ 7.5% for 9 months], eight children with T1DM-P (HbA1c ≥ 9.0% for 9 months), and eight healthy controls completed one exercise session.METHODS:
Anaerobic and aerobic muscle functions were assessed with a maximal isometric grip strength test, a Wingate test, and an incremental continuous cycling test until exhaustion. Blood samples were collected at rest to determine HbA1c at the time of testing. Physical activity was monitored over 7 d using accelerometry.RESULTS:
Children with T1DM-P displayed lower peak oxygen consumption (VO2peak ) values (mL/kg/min) compared to healthy controls (T1DM-P 33.2 ± 5.6, controls 43.5 ± 6.3, p < 0.01), while T1DM-G (43.5 ± 6.3) had values similar to controls and T1DM-P. There was a negative relationship between VO2peak and HbA1c% (r = -0.54, p < 0.01). All groups were similar in all other fitness variables. There were no group differences in physical activity variables.CONCLUSION:
Children with T1DM-G did not display signs of impaired muscle function, while children with T1DM-P have signs of altered aerobic muscle capacity.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Glucemia
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Aptitud Física
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Diabetes Mellitus Tipo 1
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Actividad Motora
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Revista:
Pediatr Diabetes
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Canadá