Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth.

Martinez-Outschoorn, Ubaldo E; Lisanti, Michael P; Sotgia, Federica

Martinez-Outschoorn, Ubaldo E; Lisanti, Michael P; Sotgia, Federica.

Afiliación

Martinez-Outschoorn UE; Kimmel Cancer Center, Philadelphia, PA, United States.
Lisanti MP; Manchester Breast Centre & Breakthrough Breast Cancer Research Unit, Institute of Cancer Sciences, University of Manchester, UK; Manchester Centre for Cellular Metabolism (MCCM), University of Manchester, UK. Electronic address: michaelp.lisanti@gmail.com.
Sotgia F; Manchester Breast Centre & Breakthrough Breast Cancer Research Unit, Institute of Cancer Sciences, University of Manchester, UK; Manchester Centre for Cellular Metabolism (MCCM), University of Manchester, UK. Electronic address: fsotgia@gmail.com.

Semin Cancer Biol ; 25: 47-60, 2014 Apr.

Article en En | MEDLINE | ID: mdl-24486645

Asunto(s)

Metabolismo Energético; Fibroblastos/metabolismo; Neoplasias/metabolismo; Animales; Comunicación Celular; Transferencia de Energía; Humanos; Neoplasias/patología; Estrés Oxidativo; Transducción de Señal; Carga Tumoral; Microambiente Tumoral

Palabras clave

Autophagy; Catabolism; Oxidative mitochondrial metabolism; Oxidative stress; Senescence; Tumor metabolism; Warburg effect

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Metabolismo Energético / Fibroblastos / Neoplasias Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Semin Cancer Biol Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

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