Charge density influences C1 domain ligand affinity and membrane interactions.

Kelsey, Jessica S; Geczy, Tamas; Lewin, Nancy E; Kedei, Noemi; Hill, Colin S; Selezneva, Julia S; Valle, Christopher J; Woo, Wonhee; Gorshkova, Inna; Blumberg, Peter M

Kelsey, Jessica S; Geczy, Tamas; Lewin, Nancy E; Kedei, Noemi; Hill, Colin S; Selezneva, Julia S; Valle, Christopher J; Woo, Wonhee; Gorshkova, Inna; Blumberg, Peter M.

Afiliación

Kelsey JS; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Geczy T; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Lewin NE; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Kedei N; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Hill CS; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Selezneva JS; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Valle CJ; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Woo W; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.
Gorshkova I; Biomedical Engineering and Physical Science Share Resource Program, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, U.S.A.
Blumberg PM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute Building 37, Room 4048, 37 Convent Drive MSC 4255, Bethesda, MD 20892-4255, U.S.A.

Chembiochem ; 15(8): 1131-1144, 2014 May 26.

Article en En | MEDLINE | ID: mdl-24777910

Asunto(s)

Membrana Celular/metabolismo; Proteína Quinasa C-delta/química; Proteína Quinasa C-delta/metabolismo; Secuencias de Aminoácidos; Sitios de Unión; Línea Celular Tumoral; Membrana Celular/química; Humanos; Ligandos; Proteína Quinasa C-delta/genética; Estructura Terciaria de Proteína; Electricidad Estática; Relación Estructura-Actividad

Palabras clave

diacylglycerols; ingenol 3-angelate; phorbol esters; protein kinase C

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Membrana Celular / Proteína Quinasa C-delta Límite: Humans Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google