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Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Kemp, John P; Medina-Gomez, Carolina; Estrada, Karol; St Pourcain, Beate; Heppe, Denise H M; Warrington, Nicole M; Oei, Ling; Ring, Susan M; Kruithof, Claudia J; Timpson, Nicholas J; Wolber, Lisa E; Reppe, Sjur; Gautvik, Kaare; Grundberg, Elin; Ge, Bing; van der Eerden, Bram; van de Peppel, Jeroen; Hibbs, Matthew A; Ackert-Bicknell, Cheryl L; Choi, Kwangbom; Koller, Daniel L; Econs, Michael J; Williams, Frances M K; Foroud, Tatiana; Zillikens, M Carola; Ohlsson, Claes; Hofman, Albert; Uitterlinden, André G; Davey Smith, George; Jaddoe, Vincent W V; Tobias, Jonathan H; Rivadeneira, Fernando; Evans, David M.
Afiliación
  • Kemp JP; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.
  • Medina-Gomez C; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics
  • Estrada K; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
  • St Pourcain B; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom; School of Experimental Psychology, University of Bristol, Bristol, United Kingdom.
  • Heppe DH; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Paediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Warrington NM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.
  • Oei L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands.
  • Ring SM; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.
  • Kruithof CJ; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Timpson NJ; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.
  • Wolber LE; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
  • Reppe S; Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway.
  • Gautvik K; Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway; Department of Medical Biochemistry, Oslo Deacon Hospital, Oslo, Norway.
  • Grundberg E; Department of Human Genetics, McGill University, Montréal, Canada; McGill University and Genome Québec Innovation Centre, Montréal, Canada.
  • Ge B; McGill University and Genome Québec Innovation Centre, Montréal, Canada.
  • van der Eerden B; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van de Peppel J; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Hibbs MA; Department of Computer Science, Trinity University, San Antonio, Texas, United States of America; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
  • Ackert-Bicknell CL; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
  • Choi K; The Jackson Laboratory, Bar Harbor, Maine, United States of America.
  • Koller DL; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
  • Econs MJ; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
  • Williams FM; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
  • Foroud T; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
  • Zillikens MC; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands.
  • Ohlsson C; Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Hofman A; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), The Netherlands.
  • Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics
  • Davey Smith G; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.
  • Jaddoe VW; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Paediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Tobias JH; School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
  • Rivadeneira F; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Netherlands Genomics
  • Evans DM; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.
PLoS Genet ; 10(6): e1004423, 2014 Jun.
Article en En | MEDLINE | ID: mdl-24945404

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Densidad Ósea / Factores de Intercambio de Guanina Nucleótido / Proteínas Wnt Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Male / Pregnancy Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Portadoras / Densidad Ósea / Factores de Intercambio de Guanina Nucleótido / Proteínas Wnt Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Child / Female / Humans / Male / Pregnancy Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Australia