Influence of immune responses in gene/stem cell therapies for muscular dystrophies.
Biomed Res Int
; 2014: 818107, 2014.
Article
en En
| MEDLINE
| ID: mdl-24959590
ABSTRACT
Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing the dystrophic muscle damage using gene transfer or cell therapy. Here we discussed current knowledge about involvement of immune system responses to experimental therapies in MDs.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Células Madre
/
Tratamiento Basado en Trasplante de Células y Tejidos
/
Inmunidad Innata
/
Distrofias Musculares
Límite:
Humans
Idioma:
En
Revista:
Biomed Res Int
Año:
2014
Tipo del documento:
Article
País de afiliación:
Italia