Inactivity of human ß,ß-carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment.

Li, Binxing; Vachali, Preejith P; Gorusupudi, Aruna; Shen, Zhengqing; Sharifzadeh, Hassan; Besch, Brian M; Nelson, Kelly; Horvath, Madeleine M; Frederick, Jeanne M; Baehr, Wolfgang; Bernstein, Paul S

Li, Binxing; Vachali, Preejith P; Gorusupudi, Aruna; Shen, Zhengqing; Sharifzadeh, Hassan; Besch, Brian M; Nelson, Kelly; Horvath, Madeleine M; Frederick, Jeanne M; Baehr, Wolfgang; Bernstein, Paul S.

Afiliación

Li B; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Vachali PP; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Gorusupudi A; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Shen Z; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Sharifzadeh H; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Besch BM; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Nelson K; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Horvath MM; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Frederick JM; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and.
Baehr W; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, andDepartment of Neurobiology and Anatomy, University of Utah School of Medicine, Salt Lake City, UT 84132; andDepartment of Biology, University of Utah, Salt Lake City, UT 84112.
Bernstein PS; Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, and paul.bernstein@hsc.utah.edu.

Proc Natl Acad Sci U S A ; 111(28): 10173-8, 2014 Jul 15.

Article en En | MEDLINE | ID: mdl-24982131

Asunto(s)

Dioxigenasas/metabolismo; Proteínas del Ojo/metabolismo; Luteína/metabolismo; Retina/enzimología; Xantófilas/metabolismo; Animales; Dioxigenasas/genética; Proteínas del Ojo/genética; Gutatión-S-Transferasa pi/genética; Gutatión-S-Transferasa pi/metabolismo; Humanos; Luteína/genética; Ratones; Ratones Noqueados; Retina/citología; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Especificidad de la Especie; Xantófilas/genética; Zeaxantinas

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Retina / Luteína / Xantófilas / Dioxigenasas / Proteínas del Ojo Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2014 Tipo del documento: Article

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