TRIM13 is a negative regulator of MDA5-mediated type I interferon production.

Narayan, Kavitha; Waggoner, Lisa; Pham, Serena T; Hendricks, Gabriel L; Waggoner, Stephen N; Conlon, Joseph; Wang, Jennifer P; Fitzgerald, Katherine A; Kang, Joonsoo

Narayan, Kavitha; Waggoner, Lisa; Pham, Serena T; Hendricks, Gabriel L; Waggoner, Stephen N; Conlon, Joseph; Wang, Jennifer P; Fitzgerald, Katherine A; Kang, Joonsoo.

Afiliación

Narayan K; Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Waggoner L; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Pham ST; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Hendricks GL; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Waggoner SN; Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Conlon J; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Wang JP; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Fitzgerald KA; Division of Infectious Diseases and Immunology, Program in Innate Immunity, University of Massachusetts Medical School, Worcester, Massachusetts, USA Kate.Fitzgerald@umassmed.edu Joonsoo.Kang@umassmed.edu.
Kang J; Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, USA Kate.Fitzgerald@umassmed.edu Joonsoo.Kang@umassmed.edu.

J Virol ; 88(18): 10748-57, 2014 Sep.

Article en En | MEDLINE | ID: mdl-25008915

Asunto(s)

Infecciones por Cardiovirus/enzimología; ARN Helicasas DEAD-box/metabolismo; Proteínas de Unión al ADN/metabolismo; Regulación hacia Abajo; Virus de la Encefalomiocarditis/fisiología; Interferón-alfa/metabolismo; Interferón beta/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo; Animales; Infecciones por Cardiovirus/genética; Infecciones por Cardiovirus/metabolismo; Infecciones por Cardiovirus/virología; ARN Helicasas DEAD-box/genética; Proteínas de Unión al ADN/genética; Femenino; Fibroblastos/enzimología; Fibroblastos/metabolismo; Fibroblastos/virología; Humanos; Factor 3 Regulador del Interferón/genética; Factor 3 Regulador del Interferón/metabolismo; Helicasa Inducida por Interferón IFIH1; Interferón-alfa/genética; Interferón beta/genética; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Proteínas de Motivos Tripartitos; Ubiquitina-Proteína Ligasas/genética

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación hacia Abajo / Interferón beta / Interferón-alfa / Infecciones por Cardiovirus / Ubiquitina-Proteína Ligasas / Proteínas de Unión al ADN / Virus de la Encefalomiocarditis / ARN Helicasas DEAD-box Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: J Virol Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google