Fatal Burkholderia pseudomallei infection initially reported as a Bacillus species, Ohio, 2013.
Am J Trop Med Hyg
; 91(4): 743-6, 2014 Oct.
Article
en En
| MEDLINE
| ID: mdl-25092821
ABSTRACT
A fatal case of melioidosis was diagnosed in Ohio one month after culture results were initially reported as a Bacillus species. To identify a source of infection and assess risk in patient contacts, we abstracted patient charts; interviewed physicians and contacts; genetically characterized the isolate; performed a Burkholderia pseudomallei antibody indirect hemagglutination assay on household contacts and pets to assess seropositivity; and collected household plant, soil, liquid, and insect samples for culturing and real-time polymerase chain reaction testing. Family members and pets tested were seronegative for B. pseudomallei. Environmental samples were negative by real-time polymerase chain reaction and culture. Although the patient never traveled internationally, the isolate genotype was consistent with an isolate that originated in Southeast Asia. This investigation identified the fifth reported locally acquired non-laboratory melioidosis case in the contiguous United States. Physicians and laboratories should be aware of this potentially emerging disease and refer positive cultures to a Laboratory Response Network laboratory.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Burkholderia pseudomallei
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Melioidosis
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Anticuerpos Antibacterianos
Tipo de estudio:
Prognostic_studies
Límite:
Adult
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Humans
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Male
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2014
Tipo del documento:
Article