Abnormal dosage of ultraconserved elements is highly disfavored in healthy cells but not cancer cells.

McCole, Ruth B; Fonseka, Chamith Y; Koren, Amnon; Wu, C-Ting

McCole, Ruth B; Fonseka, Chamith Y; Koren, Amnon; Wu, C-Ting.

Afiliación

McCole RB; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
Fonseka CY; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Biological and Biomedical Sciences PhD program, Harvard Medical School, Boston, Massachusetts, United States of America.
Koren A; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.
Wu CT; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

PLoS Genet ; 10(10): e1004646, 2014 Oct.

Article en En | MEDLINE | ID: mdl-25340765

Asunto(s)

Secuencia Conservada/genética; Variaciones en el Número de Copia de ADN/genética; Evolución Molecular; Neoplasias/genética; Animales; Paseo de Cromosoma; Dosificación de Gen; Genoma Humano; Humanos; Células Madre Pluripotentes Inducidas; Mamíferos; Neoplasias/patología; Células Madre Pluripotentes/citología; Eliminación de Secuencia

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Secuencia Conservada / Evolución Molecular / Variaciones en el Número de Copia de ADN / Neoplasias Límite: Animals / Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

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