Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells.

Tuohetahuntila, Maidina; Spee, Bart; Kruitwagen, Hedwig S; Wubbolts, Richard; Brouwers, Jos F; van de Lest, Chris H; Molenaar, Martijn R; Houweling, Martin; Helms, J Bernd; Vaandrager, Arie B

Tuohetahuntila, Maidina; Spee, Bart; Kruitwagen, Hedwig S; Wubbolts, Richard; Brouwers, Jos F; van de Lest, Chris H; Molenaar, Martijn R; Houweling, Martin; Helms, J Bernd; Vaandrager, Arie B.

Afiliación

Tuohetahuntila M; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: T.Maidina@uu.nl.
Spee B; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: B.Spee@uu.nl.
Kruitwagen HS; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands. Electronic address: H.S.Kruitwagen@uu.nl.
Wubbolts R; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: r.wubbolts@uu.nl.
Brouwers JF; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: j.brouwers@uu.nl.
van de Lest CH; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: C.H.A.vandeLest@uu.nl.
Molenaar MR; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: m.r.molenaar@uu.nl.
Houweling M; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: M.Houweling@uu.nl.
Helms JB; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: J.B.Helms@uu.nl.
Vaandrager AB; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine & Institute of Biomembranes, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: A.B.Vaandrager@uu.nl.

Biochim Biophys Acta ; 1851(2): 220-30, 2015 Feb.

Article en En | MEDLINE | ID: mdl-25500141

Asunto(s)

Coenzima A Ligasas/metabolismo; Ácidos Grasos Insaturados/metabolismo; Células Estrelladas Hepáticas/enzimología; Triglicéridos/metabolismo; Animales; Ácido Araquidónico/metabolismo; Línea Celular; Coenzima A Ligasas/antagonistas & inhibidores; Coenzima A Ligasas/genética; Inhibidores Enzimáticos/farmacología; Células Estrelladas Hepáticas/efectos de los fármacos; Humanos; Masculino; Fosfatidilcolinas/metabolismo; Interferencia de ARN; Ratas Wistar; Rosiglitazona; Tiazolidinedionas/farmacología; Factores de Tiempo; Transfección; Regulación hacia Arriba

Palabras clave

Arachidonic acid; Eicosanoid; Heavy isotope labeling; Lipidomics; Phosphatidylcholine; Prostaglandin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Triglicéridos / Coenzima A Ligasas / Células Estrelladas Hepáticas / Ácidos Grasos Insaturados Límite: Animals / Humans / Male Idioma: En Revista: Biochim Biophys Acta Año: 2015 Tipo del documento: Article

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