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Proposed method for dimensionality reduction based on framework in gene expression domain.
Macedo, D C; Ishikawa, E C M; Santos, C B; Matos, S N; Borges, H B; Francisco, A C.
Afiliación
  • Macedo DC; Anhui Provincial Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Bio-Breeding, Department of Animal Science, College of Animal Science and Technology, Anhui Agricultural University, Hefei City, Anhui, China dayanamacedo@yahoo.com.br.
  • Ishikawa EC; Department of Veterinary, College of Animal Science and Technology, Anhui Agricultural University, Hefei City, Anhui, China.
  • Santos CB; Department of Internal Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China.
  • Matos SN; Department of Traditional Chinese Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China.
  • Borges HB; Centro de Atualização em Saúde, São Paulo, SP, Brasil.
  • Francisco AC; Programa de Pós-graduação em Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinária, Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, SP, Brasil.
Genet Mol Res ; 13(4): 10582-91, 2014 Dec 12.
Article en En | MEDLINE | ID: mdl-25511043
ABSTRACT
The excessive use of attributes may affect the search for patterns and extraction of useful knowledge, because they harm the learning performance of algorithms in both speed and success rate. The use of dimensionality reduction methods is therefore an important alternative; however, these methods do not deal with the reduction of attributes in a specific area. This article presents a method based on framework concepts of domain for reducing attributes in a domain. The input method is a set of databases related to a domain, and the main process is the identification of common and variable attributes, plus the reduction of attributes in the original database. The proposed method was applied in the gene expression domain, using databases. The method can be used to analyze the most relevant attributes in a specific domain, granting greater confidence for models created for the application of a data mining task, thus, a previously known method in data mining. Attribute selection was also applied in the three databases for the comparison of the results. Analyses of the results using the criterion of cross-validation revealed that the employment of the methods resulted in the improvement of success rates compared to the databases containing the full range of attributes.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Algoritmos / Bases de Datos Genéticas / Minería de Datos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genet Mol Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2014 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Algoritmos / Bases de Datos Genéticas / Minería de Datos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genet Mol Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2014 Tipo del documento: Article País de afiliación: China