Noise-optimized virtual monoenergetic images and iodine maps for the detection of venous thrombosis in second-generation dual-energy CT (DECT): an ex vivo phantom study.
Eur Radiol
; 25(6): 1655-64, 2015 Jun.
Article
en En
| MEDLINE
| ID: mdl-25528670
ABSTRACT
AIMS AND OBJECTIVES:
Deep venous thrombosis (DVT) can be difficult to detect using CT due to poor and heterogeneous contrast. Dual-energy CT (DECT) allows iodine contrast optimization using noise-optimized monoenergetic extrapolations (MEIs) and iodine maps (IMs). Our aim was to assess whether MEI and IM could improve the delineation of thrombotic material within iodine-enhanced blood compared to single-energy CT (SECT). MATERIALS ANDMETHODS:
Six vessel phantoms, including human thrombus and contrast media-enhanced blood and one phantom without contrast, were placed in an attenuation phantom and scanned with DECT 100/140 kV and SECT 120 kV. IM, virtual non-contrast images (VNC), mixed images, and MEI were calculated. Attenuation of thrombi and blood were measured. Contrast and contrast-to-noise-ratios (CNRs) were calculated and compared among IM, VNC, mixed images, MEI, and SECT using paired t tests.RESULTS:
MEI40keV and IM showed significantly higher contrast and CNR than SE120kV from high to intermediate iodine concentrations (contrastpMEI40keV < 0.002,pIM < 0.005;CNRpMEI40keV < 0.002,pIM < 0.004). At low iodine concentrations, MEI190keV and VNC images showed significantly higher contrast and CNR than SE120kV with inverted contrasts (contrastpMEI190keV < 0.008,pVNC < 0.002;CNRpMEI190keV < 0.003,pVNC < 0.002).CONCLUSIONS:
Noise-optimized MEI and IM provide significantly higher contrast and CNR in the delineation of thrombosis compared to SECT, which may facilitate the detection of DVT in difficult cases. KEY POINTS ⢠Poor contrast makes it difficult to detect thrombosis in CT. ⢠Dual-energy-CT allows contrast optimization using monoenergetic extrapolations (MEI) and iodine maps (IM). ⢠Noise-optimized-MEI and IM are significantly superior to single-energy-CT in delineation of thrombosis. ⢠Noise-optimized-MEI and IM may facilitate the detection of deep vein thrombosis.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Intensificación de Imagen Radiográfica
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Tomografía Computarizada por Rayos X
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Fantasmas de Imagen
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Trombosis de la Vena
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Yodo
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Alemania