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Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.
Rombouts, Yoann; Willemze, Annemiek; van Beers, Joyce J B C; Shi, Jing; Kerkman, Priscilla F; van Toorn, Linda; Janssen, George M C; Zaldumbide, Arnaud; Hoeben, Rob C; Pruijn, Ger J M; Deelder, André M; Wolbink, Gertjan; Rispens, Theo; van Veelen, Peter A; Huizinga, Tom W J; Wuhrer, Manfred; Trouw, Leendert A; Scherer, Hans U; Toes, René E M.
Afiliación
  • Rombouts Y; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • Willemze A; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • van Beers JJ; Radboud Institute for Molecular Life Sciences and Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.
  • Shi J; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Kerkman PF; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • van Toorn L; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Janssen GM; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands Netherlands Proteomics Centre, Utrecht, the Netherlands.
  • Zaldumbide A; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Hoeben RC; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Pruijn GJ; Radboud Institute for Molecular Life Sciences and Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.
  • Deelder AM; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • Wolbink G; Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, the Netherlands Jan van Breemen Research Institute Reade, Amsterdam, the Netherlands.
  • Rispens T; Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, the Netherlands.
  • van Veelen PA; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Huizinga TW; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Wuhrer M; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands.
  • Trouw LA; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Scherer HU; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Toes RE; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.
Ann Rheum Dis ; 75(3): 578-85, 2016 Mar.
Article en En | MEDLINE | ID: mdl-25587188
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polisacáridos / Artritis Reumatoide / Autoanticuerpos / Autoantígenos / Glicosilación / Inmunoglobulina G / Citrulina Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Polisacáridos / Artritis Reumatoide / Autoanticuerpos / Autoantígenos / Glicosilación / Inmunoglobulina G / Citrulina Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos