Identification and characterization of a novel tick-borne flavivirus subtype in goats (Capra hircus) in Spain.
J Gen Virol
; 96(Pt 7): 1676-81, 2015 Jul.
Article
en En
| MEDLINE
| ID: mdl-25701823
ABSTRACT
In 2011, a neurological disease was reported in a herd of goats (Capra hircus) in Asturias, Spain. Initial sequencing identified the causative agent as louping ill virus (LIV). Subsequently, with the application of whole genome sequencing and phylogenetic analysis, empirical data demonstrates that the LIV-like virus detected is significantly divergent from LIV and Spanish sheep encephalitis virus (SSEV). This virus encoded an amino acid sequence motif at the site of a previously identified marker for differentiating tick-borne flaviviruses that was shared with a virus previously isolated in Ireland in 1968. The significance of these observations reflects the diversity of tick-borne flaviviruses in Europe. These data also contribute to our knowledge of the evolution of tick-borne flaviviruses and could reflect the movement of viruses throughout Europe. Based on these observations, the proposed name for this virus is Spanish goat encephalitis virus (SGEV), to distinguish it from SSEV.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
ARN Viral
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Cabras
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Enfermedades de las Cabras
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Genoma Viral
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Análisis de Secuencia de ADN
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Encefalitis Transmitida por Garrapatas
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Virus de la Encefalitis Transmitidos por Garrapatas
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Gen Virol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Reino Unido