Melatonin-mediated inhibition of Purkinje neuron P-type Ca²âº channels in vitro induces neuronal hyperexcitability through the phosphatidylinositol 3-kinase-dependent protein kinase C delta pathway.

Zhang, Yuan; Li, Hua; Pu, Yicheng; Gong, Shan; Liu, Chunfeng; Jiang, Xinghong; Tao, Jin

Melatonin-mediated inhibition of Purkinje neuron P-type Ca²âº channels in vitro induces neuronal hyperexcitability through the phosphatidylinositol 3-kinase-dependent protein kinase C delta pathway.

Zhang, Yuan; Li, Hua; Pu, Yicheng; Gong, Shan; Liu, Chunfeng; Jiang, Xinghong; Tao, Jin.

Afiliación

Zhang Y; Department of Neurobiology, Medical College of Soochow University, Suzhou, China; Department of Geriatrics and Institute of Neuroscience, The Second Affiliated Hospital of Soochow University, Suzhou, China.

J Pineal Res ; 58(3): 321-34, 2015 Apr.

Article en En | MEDLINE | ID: mdl-25707622

Asunto(s)

Canales de Calcio Tipo P/efectos de los fármacos; Melatonina/farmacología; Fosfatidilinositol 3-Quinasa/metabolismo; Proteína Quinasa C-delta/metabolismo; Células de Purkinje/efectos de los fármacos; Animales; Canales de Calcio Tipo P/metabolismo; Células de Purkinje/metabolismo; Ratas; Ratas Wistar

Palabras clave

P-type calcium channel; Purkinje neuron; melatonin; protein kinase C

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células de Purkinje / Canales de Calcio Tipo P / Proteína Quinasa C-delta / Fosfatidilinositol 3-Quinasa / Melatonina Límite: Animals Idioma: En Revista: J Pineal Res Asunto de la revista: ENDOCRINOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: China

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