Radiation necrosis presenting as pseudoprogression (PsP) during alectinib treatment of previously radiated brain metastases in ALK-positive NSCLC: Implications for disease assessment and management.

Ou, Sai-Hong Ignatius; Klempner, Samuel J; Azada, Michele C; Rausei-Mills, Veronica; Duma, Christopher

Ou, Sai-Hong Ignatius; Klempner, Samuel J; Azada, Michele C; Rausei-Mills, Veronica; Duma, Christopher.

Afiliación

Ou SH; Department of Medicine, Division of Hematology-Oncology, University of California Irvine School of Medicine, Orange, CA 92868, United States; Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, United States. Electronic address: Ignatius.ou@uci.
Klempner SJ; Department of Medicine, Division of Hematology-Oncology, University of California Irvine School of Medicine, Orange, CA 92868, United States; Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, United States.
Azada MC; Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, United States.
Rausei-Mills V; Department of Pathology, Hoag Memorial Hospital Presbyterian, One Hoag Drive, Newport Beach, CA 92658, United States.
Duma C; Hoag Neurosciences Institute, Director, Hoag Brain Tumor Program, Hoag Memorial Hospital Presbyterian, Newport Beach, CA 92663, United States.

Lung Cancer ; 88(3): 355-9, 2015 Jun.

Article en En | MEDLINE | ID: mdl-25882777

Asunto(s)

Neoplasias Encefálicas/diagnóstico; Neoplasias Encefálicas/secundario; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/patología; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; Proteínas Tirosina Quinasas Receptoras/metabolismo; Adulto; Quinasa de Linfoma Anaplásico; Biopsia; Neoplasias Encefálicas/tratamiento farmacológico; Neoplasias Encefálicas/radioterapia; Progresión de la Enfermedad; Femenino; Humanos; Imagen por Resonancia Magnética; Masculino; Persona de Mediana Edad; Necrosis/diagnóstico; Necrosis/etiología

Palabras clave

Alectinib; Anaplastic lymphoma kinase-rearranged non-small cell lung cancer; Brain metastasis; Pseudoprogression; Radiation necrosis; Response assessment in neuro-oncology (RANO)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Proteínas Tirosina Quinasas Receptoras / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lung Cancer Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article

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