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Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
Mitchell, Jacqueline C; Constable, Remy; So, Eva; Vance, Caroline; Scotter, Emma; Glover, Leanne; Hortobagyi, Tibor; Arnold, Eveline S; Ling, Shuo-Chien; McAlonis, Melissa; Da Cruz, Sandrine; Polymenidou, Magda; Tessarolo, Lino; Cleveland, Don W; Shaw, Christopher E.
Afiliación
  • Mitchell JC; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. jacqueline.mitchell@kcl.ac.uk.
  • Constable R; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. remy.constable@kcl.ac.uk.
  • So E; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. eva.so@kcl.ac.uk.
  • Vance C; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. caroline.vance@kcl.ac.uk.
  • Scotter E; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. emma.scotter@kcl.ac.uk.
  • Glover L; Centre for Ultrastructural Imaging, Kings College London, London, SE1 1UL, UK. leanne.glover@kcl.ac.uk.
  • Hortobagyi T; King's Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences, Institute of Psychiatry, Psychology and Neuroscience, London, SE5 8AF, UK. tibor.hortobagyi@kcl.ac.uk.
  • Arnold ES; Ludwig Institute for Cancer Research and Department of Molecular Medicine, University of California at San Diego, La Jolla, CA, 92093, USA. ejsun@ucsd.edu.
  • Ling SC; Present address: Neurogenetics Branch, NINDS, National Institutes of Health, Bethesda, MD, 20892, USA. ejsun@ucsd.edu.
  • McAlonis M; Ludwig Institute for Cancer Research and Department of Molecular Medicine, University of California at San Diego, La Jolla, CA, 92093, USA. sling@ucsd.edu.
  • Da Cruz S; Ludwig Institute for Cancer Research and Department of Molecular Medicine, University of California at San Diego, La Jolla, CA, 92093, USA. mmcalonis@ucsd.edu.
  • Polymenidou M; Ludwig Institute for Cancer Research and Department of Molecular Medicine, University of California at San Diego, La Jolla, CA, 92093, USA. sdacruz@ucsd.edu.
  • Tessarolo L; Ludwig Institute for Cancer Research and Department of Molecular Medicine, University of California at San Diego, La Jolla, CA, 92093, USA. magdalini.polymenidou@imls.uzh.ch.
  • Cleveland DW; Present address: Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland. magdalini.polymenidou@imls.uzh.ch.
  • Shaw CE; Mouse Cancer Genetics Program, National Cancer Institute - Frederick, Frederick, MD, 21702, USA. tessarol@mail.nih.gov.
Acta Neuropathol Commun ; 3: 36, 2015 Jun 25.
Article en En | MEDLINE | ID: mdl-26108367
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Corteza Cerebral / Proteínas de Unión al ADN / Esclerosis Amiotrófica Lateral / Mutación / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Commun Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Corteza Cerebral / Proteínas de Unión al ADN / Esclerosis Amiotrófica Lateral / Mutación / Neuronas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Acta Neuropathol Commun Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido