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Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells.
Karkashon, Shay; Raghupathy, Radha; Bhatia, Himanshu; Dutta, Amrita; Hess, Sonja; Higgs, Jaimie; Tifft, Cynthia J; Little, Jane A.
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  • Karkashon S; Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States.
  • Raghupathy R; Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States.
  • Bhatia H; Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States.
  • Dutta A; Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States.
  • Hess S; California Institute of Technology, Beckman Institute, Proteome Exploration Laboratory, 1200 E California Blvd, MC139-74, Pasadena, CA 91125, United States.
  • Higgs J; Division of Genetics and Metabolism, Center for Hospital-based Specialties, Children's National Medical Center, 111 Michigan Ave. N.W., Washington, DC 20010-2970, United States.
  • Tifft CJ; Division of Genetics and Metabolism, Center for Hospital-based Specialties, Children's National Medical Center, 111 Michigan Ave. N.W., Washington, DC 20010-2970, United States.
  • Little JA; Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States. Electronic address: Jane.little@uhhospitals.org.
Blood Cells Mol Dis ; 55(2): 161-7, 2015 Aug.
Article en En | MEDLINE | ID: mdl-26142333
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hemoglobina Fetal / Proteínas Nucleares / Proteínas Portadoras / Células Eritroides / Factores de Transcripción SOXD / Aminoácidos de Cadena Ramificada Tipo de estudio: Prognostic_studies Límite: Child / Child, preschool / Humans Idioma: En Revista: Blood Cells Mol Dis Asunto de la revista: HEMATOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Hemoglobina Fetal / Proteínas Nucleares / Proteínas Portadoras / Células Eritroides / Factores de Transcripción SOXD / Aminoácidos de Cadena Ramificada Tipo de estudio: Prognostic_studies Límite: Child / Child, preschool / Humans Idioma: En Revista: Blood Cells Mol Dis Asunto de la revista: HEMATOLOGIA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos