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Versatile Multicomponent Reaction Macrocycle Synthesis Using α-Isocyano-ω-carboxylic Acids.
Liao, George P; Abdelraheem, Eman M M; Neochoritis, Constantinos G; Kurpiewska, Katarzyna; Kalinowska-Tluscik, Justyna; McGowan, David C; Dömling, Alexander.
Afiliación
  • Liao GP; Department of Drug Design, University of Groningen , A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Abdelraheem EM; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium.
  • Neochoritis CG; Department of Drug Design, University of Groningen , A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Kurpiewska K; Chemistry Department, Faculty of Science, Sohag University , Sohag 82524, Egypt.
  • Kalinowska-Tluscik J; Department of Drug Design, University of Groningen , A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • McGowan DC; Faculty of Chemistry, Jagiellonian University , 3 Ingardena Street, 30-060 Kraków, Poland.
  • Dömling A; Faculty of Chemistry, Jagiellonian University , 3 Ingardena Street, 30-060 Kraków, Poland.
Org Lett ; 17(20): 4980-3, 2015 Oct 16.
Article en En | MEDLINE | ID: mdl-26439710
The direct macrocycle synthesis of α-isocyano-ω-carboxylic acids via an Ugi multicomponent reaction is introduced. This multicomponent reaction (MCR) protocol differs by being especially short, convergent, and versatile, giving access to 12-22 membered rings.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos Carboxílicos / Compuestos Macrocíclicos Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos Carboxílicos / Compuestos Macrocíclicos Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Países Bajos