Assessment of Venous Thrombosis in Animal Models.
Arterioscler Thromb Vasc Biol
; 36(2): 245-52, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26681755
ABSTRACT
Deep vein thrombosis and common complications, including pulmonary embolism and post-thrombotic syndrome, represent a major source of morbidity and mortality worldwide. Experimental models of venous thrombosis have provided considerable insight into the cellular and molecular mechanisms that regulate thrombus formation and subsequent resolution. Here, we critically appraise the ex vivo and in vivo techniques used to assess venous thrombosis in these models. Particular attention is paid to imaging modalities, including magnetic resonance imaging, micro-computed tomography, and high-frequency ultrasound that facilitate longitudinal assessment of thrombus size and composition.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Venas
/
Trombosis de la Vena
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Arterioscler Thromb Vasc Biol
Asunto de la revista:
ANGIOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Reino Unido