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Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice.
Linch, Stefanie N; Kasiewicz, Melissa J; McNamara, Michael J; Hilgart-Martiszus, Ian F; Farhad, Mohammad; Redmond, William L.
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  • Linch SN; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213;
  • Kasiewicz MJ; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213;
  • McNamara MJ; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213;
  • Hilgart-Martiszus IF; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213;
  • Farhad M; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213; Cell, Developmental, and Cancer Biology Department, Oregon Health and Science University, Portland, OR 97239.
  • Redmond WL; Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR 97213; william.redmond@providence.org.
Proc Natl Acad Sci U S A ; 113(3): E319-27, 2016 Jan 19.
Article en En | MEDLINE | ID: mdl-26729864
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunación / Anergia Clonal / Receptor ErbB-2 / Receptores OX40 / Antígeno CTLA-4 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunación / Anergia Clonal / Receptor ErbB-2 / Receptores OX40 / Antígeno CTLA-4 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2016 Tipo del documento: Article