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CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma.
Noll, Elisa M; Eisen, Christian; Stenzinger, Albrecht; Espinet, Elisa; Muckenhuber, Alexander; Klein, Corinna; Vogel, Vanessa; Klaus, Bernd; Nadler, Wiebke; Rösli, Christoph; Lutz, Christian; Kulke, Michael; Engelhardt, Jan; Zickgraf, Franziska M; Espinosa, Octavio; Schlesner, Matthias; Jiang, Xiaoqi; Kopp-Schneider, Annette; Neuhaus, Peter; Bahra, Marcus; Sinn, Bruno V; Eils, Roland; Giese, Nathalia A; Hackert, Thilo; Strobel, Oliver; Werner, Jens; Büchler, Markus W; Weichert, Wilko; Trumpp, Andreas; Sprick, Martin R.
Afiliación
  • Noll EM; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Eisen C; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Stenzinger A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Espinet E; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Muckenhuber A; Department of Pathology, University of Heidelberg, Heidelberg, Germany.
  • Klein C; National Center for Tumor Diseases (NCT), Heidelberg, Germany.
  • Vogel V; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Klaus B; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Nadler W; Department of Pathology, University of Heidelberg, Heidelberg, Germany.
  • Rösli C; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Lutz C; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Kulke M; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
  • Engelhardt J; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Zickgraf FM; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Espinosa O; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Schlesner M; Heidelberg Pharma GmbH, Ladenburg, Germany.
  • Jiang X; Heidelberg Pharma GmbH, Ladenburg, Germany.
  • Kopp-Schneider A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Neuhaus P; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bahra M; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
  • Sinn BV; Divison of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Eils R; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Giese NA; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Hackert T; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.
  • Strobel O; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.
  • Werner J; Department of General, Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Büchler MW; Department of General, Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Weichert W; Institute of Pathology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Trumpp A; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Sprick MR; Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany.
Nat Med ; 22(3): 278-87, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26855150
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Resistencia a Antineoplásicos / Carcinoma Ductal Pancreático / Citocromo P-450 CYP3A / Factor Nuclear 1-alfa del Hepatocito / Queratinas Específicas del Pelo / Queratinas Tipo II Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Resistencia a Antineoplásicos / Carcinoma Ductal Pancreático / Citocromo P-450 CYP3A / Factor Nuclear 1-alfa del Hepatocito / Queratinas Específicas del Pelo / Queratinas Tipo II Tipo de estudio: Prognostic_studies Límite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Alemania